Chemoradiotherapy for Cervical Cancer in 2010

被引：0
作者：
Ann H. Klopp
Patricia J. Eifel
机构：
[1] The University of Texas MD Anderson Cancer Center,Department of Radiation Oncology
来源：
Current Oncology Reports | 2011年 / 13卷
关键词：
Cervical cancer; Cisplatin; Radiotherapy; Chemoradiotherapy; Brachytherapy;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
The introduction of concurrent chemotherapy and radiotherapy for the definitive treatment of cervical cancer constituted a major advance in the management of cervical cancer, resulting in a significant improvement in local control, progression-free survival, and overall survival. Since the publication of the results of seminal trials demonstrating the benefits of platinum-based chemotherapy, investigations of new cytotoxic and targeting agents have continued. The success of these studies has been limited in part because the side effects of standard platinum-based chemoradiation regimens already approach the limits of tolerability. Future progress will depend on identifying new agents without overlapping toxic effects, improving supportive care, and minimizing the toxic effects of radiation.
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页码：77 / 85
页数：8
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