Blocking podoplanin suppresses growth and pulmonary metastasis of human malignant melanoma

被引:0
作者
Mengqiao Xu
Xia Wang
Yanfang Pan
Xingpeng Zhao
Bin Yan
Changgeng Ruan
Lijun Xia
Yiming Zhao
机构
[1] The First Affiliated Hospital of Soochow University,Jiangsu Institute of Hematology, Key Laboratory of Thrombosis and Hemostasis of the Ministry of Health
[2] Soochow University,Collaborative Innovation Center of Hematology
[3] The Affiliated Suzhou Hospital of Nanjing Medical University,Clinical Laboratory Center
[4] Drug Farm. Inc,State Key Laboratory of Radiation Medicine and Protection
[5] Luoyang Central Hospital Affiliated to Zhengzhou University,undefined
[6] Soochow University,undefined
来源
BMC Cancer | / 19卷
关键词
Podoplanin; Antibody-based therapy; Malignant melanoma; Metastasis; Tumor growth;
D O I
暂无
中图分类号
学科分类号
摘要
引用
收藏
相关论文
共 113 条
[1]  
Lowe KL(2012)Platelet CLEC-2 and podoplanin in cancer metastasis Thromb Res 129 S30-S37
[2]  
Navarro-Nunez L(2016)Involvement of platelets in tumor cell metastasis Pharmacol Ther 157 112-119
[3]  
Waston SP(2004)Platelets and metastasis revisited: a novel fatty link J Clin Invest 114 1691-1693
[4]  
Tesfamariam B(2014)Mechanistic explanation for platelet contribution to cancer metastasis Thromb Res 133 S149-S157
[5]  
Gupta GP(2005)Up-regulation of the lymphatic marker podoplanin, a mucin-type transmembrane glycoprotein, in human squamous cell carcinomas and germ cell tumors Am J Pathol 166 913-921
[6]  
Massague J(2006)Tumor invasion in the absence of epithelial-mesenchymal transition: podoplanin-mediated remodeling of the actin cytoskeleton Cancer Cell 9 261-272
[7]  
Stegner D(2006)Overexpression of podoplanin in oral cancer and its association with poor clinical outcome Cancer. 107 563-569
[8]  
Dutting S(2005)Podoplanin as a marker for mesothelioma Pathol Int 55 83-86
[9]  
Nieswandt B(2005)D2-40 and podoplanin are highly specific and sensitive immunohistochemical markers of epithelioid malignant mesothelioma Hum Pathol 36 372-380
[10]  
Schacht V(1999)Expression of vascular endothelial growth factor receptor-3 and podoplanin suggests a lymphatic endothelial cell origin of Kaposi's sarcoma tumor cells Lab Invest 79 243-251