The NLRP3 inflammasome: a vital player in inflammation and mediating the anti-inflammatory effect of CBD

[1] Martinon F(2002)The inflammasome: a molecular platform triggering activation of inflammatory caspases and processing of proIL-beta Mol Cell 10 417-426

[2] Burns K(2004)NALP3 forms an IL-1beta-processing inflammasome with increased activity in Muckle–Wells autoinflammatory disorder Immunity 20 319-325

[3] Tschopp J(2023)Clonal haematopoiesis and risk of chronic liver disease Nature 616 747-754

[4] Agostini L(2023)The NLRP3 inflammasome: contributions to inflammation-related diseases Cell Mol Biol Lett 28 51-297.e10

[5] Martinon F(2023)Palmitoylation prevents sustained inflammation by limiting NLRP3 inflammasome activation through chaperone-mediated autophagy Mol Cell 83 281-1471

[6] Burns K(2023)Deubiquitinase OTUD6A in macrophages promotes intestinal inflammation and colitis via deubiquitination of NLRP3 Cell Death Differ 30 1457-305

[7] McDermott MF(2001)Mutation of a new gene encoding a putative pyrin-like protein causes familial cold autoinflammatory syndrome and Muckle–Wells syndrome Nat Genet 29 301-2452

[8] Hawkins PN(2002)Association of mutations in the NALP3/CIAS1/PYPAF1 gene with a broad phenotype including recurrent fever, cold sensitivity, sensorineural deafness, and AA amyloidosis Arthritis Rheum 46 2445-3348

[9] Tschopp J(2002)De novo CIAS1 mutations, cytokine activation, and evidence for genetic heterogeneity in patients with neonatal-onset multisystem inflammatory disease (NOMID): a new member of the expanding family of pyrin-associated autoinflammatory diseases Arthritis Rheum 46 3340-600

[10] Wong WJ(2023)Cryo-EM structures of the active NLRP3 inflammasome disc Nature 613 595-124

[1] Martinon F(2002)The inflammasome: a molecular platform triggering activation of inflammatory caspases and processing of proIL-beta Mol Cell 10 417-426

[2] Burns K(2004)NALP3 forms an IL-1beta-processing inflammasome with increased activity in Muckle–Wells autoinflammatory disorder Immunity 20 319-325

[3] Tschopp J(2023)Clonal haematopoiesis and risk of chronic liver disease Nature 616 747-754

[4] Agostini L(2023)The NLRP3 inflammasome: contributions to inflammation-related diseases Cell Mol Biol Lett 28 51-297.e10

[5] Martinon F(2023)Palmitoylation prevents sustained inflammation by limiting NLRP3 inflammasome activation through chaperone-mediated autophagy Mol Cell 83 281-1471

[6] Burns K(2023)Deubiquitinase OTUD6A in macrophages promotes intestinal inflammation and colitis via deubiquitination of NLRP3 Cell Death Differ 30 1457-305

[7] McDermott MF(2001)Mutation of a new gene encoding a putative pyrin-like protein causes familial cold autoinflammatory syndrome and Muckle–Wells syndrome Nat Genet 29 301-2452

[8] Hawkins PN(2002)Association of mutations in the NALP3/CIAS1/PYPAF1 gene with a broad phenotype including recurrent fever, cold sensitivity, sensorineural deafness, and AA amyloidosis Arthritis Rheum 46 2445-3348

[9] Tschopp J(2002)De novo CIAS1 mutations, cytokine activation, and evidence for genetic heterogeneity in patients with neonatal-onset multisystem inflammatory disease (NOMID): a new member of the expanding family of pyrin-associated autoinflammatory diseases Arthritis Rheum 46 3340-600

[10] Wong WJ(2023)Cryo-EM structures of the active NLRP3 inflammasome disc Nature 613 595-124