Pan-cancer analysis revealed H3K4me1 at bivalent promoters premarks DNA hypermethylation during tumor development and identified the regulatory role of DNA methylation in relation to histone modifications

[1] Baylin SB(2016)Epigenetic determinants of cancer Cold Spring Harb Perspect Biol 8 a019505-811

[2] Jones PA(2020)Transition to naïve human pluripotency mirrors pan-cancer DNA hypermethylation Nat Commun 11 3671-1027

[3] Patani H(2019)The DNA methylation landscape in cancer Essays Biochem 63 797-71.e16

[4] Rushton MD(2021)Navigating the DNA methylation landscape of cancer Trends Genet 37 1012-5752

[5] Higham J(2016)OVOL2, an inhibitor of WNT signaling, reduces invasive activities of human and mouse cancer cells and is down-regulated in human colorectal tumors Gastroenterology 150 659-206

[6] Teijeiro SA(2021)MTNR1B polymorphisms with CDKN2A and MGMT methylation status are associated with poor prognosis of colorectal cancer in Taiwan World J Gastroenterol 27 5737-131

[7] Oxley D(2010)DNA methylation markers in colorectal cancer Cancer Metastasis Rev 29 181-90

[8] Cutillas P(2022)Single-cell tumor-immune microenvironment of BRCA1/2 mutated high-grade serous ovarian cancer Nat Commun 13 835-1338

[9] Skvortsova K(2020)BRCA1 promoter hypermethylation is associated with good prognosis and chemosensitivity in triple-negative breast cancer Cancers (Basel) 12 828-1391

[10] Stirzaker C(2020)The bivalent genome: characterization, structure, and regulation Trends Genet 36 118-849

[1] Baylin SB(2016)Epigenetic determinants of cancer Cold Spring Harb Perspect Biol 8 a019505-811

[2] Jones PA(2020)Transition to naïve human pluripotency mirrors pan-cancer DNA hypermethylation Nat Commun 11 3671-1027

[3] Patani H(2019)The DNA methylation landscape in cancer Essays Biochem 63 797-71.e16

[4] Rushton MD(2021)Navigating the DNA methylation landscape of cancer Trends Genet 37 1012-5752

[5] Higham J(2016)OVOL2, an inhibitor of WNT signaling, reduces invasive activities of human and mouse cancer cells and is down-regulated in human colorectal tumors Gastroenterology 150 659-206

[6] Teijeiro SA(2021)MTNR1B polymorphisms with CDKN2A and MGMT methylation status are associated with poor prognosis of colorectal cancer in Taiwan World J Gastroenterol 27 5737-131

[7] Oxley D(2010)DNA methylation markers in colorectal cancer Cancer Metastasis Rev 29 181-90

[8] Cutillas P(2022)Single-cell tumor-immune microenvironment of BRCA1/2 mutated high-grade serous ovarian cancer Nat Commun 13 835-1338

[9] Skvortsova K(2020)BRCA1 promoter hypermethylation is associated with good prognosis and chemosensitivity in triple-negative breast cancer Cancers (Basel) 12 828-1391

[10] Stirzaker C(2020)The bivalent genome: characterization, structure, and regulation Trends Genet 36 118-849