Autophagy occurs in lymphocytes infiltrating Sjögren’s syndrome minor salivary glands and correlates with histological severity of salivary gland lesions

被引:0
作者
Serena Colafrancesco
Marta Vomero
Valentina Iannizzotto
Antonina Minniti
Cristiana Barbati
Francesca Arienzo
Linda Mastromanno
Tania Colasanti
Raffaella Izzo
Saba Nayar
Elena Pipi
Bruna Cerbelli
Carla Giordano
Francesco Ciccia
Fabrizio Conti
Guido Valesini
Francesca Barone
Roberta Priori
Cristiano Alessandri
机构
[1] Sapienza University of Rome,Dipartimento di Scienze Cliniche Internistiche, Anestesiologiche e Cardiovascolari
[2] University of Birmingham,Rheumatology Research Group, Institute of Inflammation and Ageing
[3] Sapienza University of Rome,Dipartimento di Radiologia, Oncologia e Scienze Patologiche
[4] University of Campania “L. Vanvitelli”,Dipartimento di Medicina di Precisione, Rheumatology Unit
[5] National Institute for Health Research (NIHR) Birmingham Biomedical Research Centre,undefined
[6] University Hospitals Birmingham NHS Foundation Trust,undefined
[7] UK and Sandwell and West Birmingham Trust,undefined
来源
Arthritis Research & Therapy | / 22卷
关键词
Autophagy; Lymphocytes; Sjögren’s syndrome; Minor salivary gland; LC3B; Atg5;
D O I
暂无
中图分类号
学科分类号
摘要
引用
收藏
相关论文
共 132 条
  • [1] Mizushima N(2018)A brief history of autophagy from cell biology to physiology and disease Nat Cell Biol 20 521-527
  • [2] Bonam SR(2018)Autophagy: a new concept in autoimmunity regulation and a novel therapeutic option J Autoimmun 94 16-32
  • [3] Wang F(2007)Structure of Atg5.Atg16, a complex essential for autophagy J Biol Chem 282 6763-6772
  • [4] Muller S(2008)LC3 and autophagy Methods Mol Biol 445 77-88
  • [5] Matsushita M(2015)Autophagosome proteins LC3A, LC3B and LC3C have distinct subcellular distribution kinetics and expression in cancer cell lines PLoS One 10 e0137675-222
  • [6] Suzuki NN(2016)Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) Autophagy 12 1-156
  • [7] Obara K(2017)Quantifying autophagy: measuring LC3 puncta and autolysosome formation in cells using multispectral imaging flow cytometry Methods 112 147-4732
  • [8] Fujioka Y(2019)Reduction of autophagy and increase in apoptosis correlates with a favourable clinical outcome in patients with rheumatoid arthritis treated with anti-TNF drugs Arthritis Res Ther 21 39-145
  • [9] Ohsumi Y(2012)T lymphocytes from patients with systemic lupus erythematosus are resistant to induction of autophagy FASEB J 26 4722-407
  • [10] Inagaki F(2017)CD4 T lymphocyte autophagy is upregulated in the salivary glands of primary Sjögren's syndrome patients and correlates with focus score and disease activity Arthritis Res Ther 19 178-170