Solubilization of Cationic Drugs in Lung Surfactant

被引：0
|
作者：
Xiangmin Liao
Timothy S. Wiedmann
机构：
[1] University of Minnesota,Department of Pharmaceutics
来源：
Pharmaceutical Research | 2003年 / 20卷
关键词：
lung surfactant; phenothiazines; pKa; partition coefficient; solubilization;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Purpose. The association of hydrophobic, cationic drugs with lung surfactant was determined to assess the pharmacokinetic implications on drug disposition and retention in the lung.
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页码：1858 / 1863
页数：5
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