Near-Infrared spectroscopy to monitor peripheral blood flow perfusion

被引:38
作者
Harel F. [1 ]
Denault A. [2 ]
Ngo Q. [1 ]
Dupuis J. [3 ]
Khairy P. [3 ]
机构
[1] Department of Nuclear Medicine, Montreal Heart Institute, Université de Montréal, Montreal, QC H1T 1C8
[2] Department of Anesthesiology, Montreal Heart Institute, Université de Montréal, Montreal, QC H1T 1C8
[3] Department of Medicine, Montreal Heart Institute, Université de Montréal, Montreal, QC H1T 1C8
关键词
Near-infrared spectroscopy; Peripheral perfusion; Reactive hyperemia;
D O I
10.1007/s10877-007-9105-9
中图分类号
学科分类号
摘要
Background: Non-invasive evaluation of peripheral perfusion may be useful in many contexts including peri-operative monitoring. We validated a novel non-invasive spectroscopy technique to assess peripheral perfusion. This method, which is based on the measurement of tissue saturation variations after an ischemic period, was compared to strain gauge plethysmography and radionuclide plethysmography. The technique uses near-infrared spectroscopy (NIRS) to determine the rate of change of forearm tissue saturation during reactive hyperemia. Methods: In a prospective crossover study, 25 subjects were simultaneously evaluated with NIRS and strain gauge plethysmography. Six baseline flow measurements were performed to assess the reproducibility of each method. Twenty-seven serial measurements were then made to evaluate flow variation during forearm reactive hyperemia. Results: Strain gauge and NIRS methods showed excellent reproducibility with intra-class correlation coefficients of 0.96 and 0.93, respectively. Conclusion: The NIRS technique appears well suited for the non-invasive evaluation of limb perfusion. © Springer Science+Business Media B.V. 2007.
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页码:37 / 43
页数:6
相关论文
共 27 条
[1]  
Joyner MJ, Dietz NM, Shepherd JT, From Belfast to Mayo and beyond: the use and future of plethysmography to study blood flow in human limbs, J Appl Physiol, 91, pp. 2431-2441, (2001)
[2]  
Wilkinson IB, Webb DJ, Venous occlusion plethysmography in cardiovascular research: methodology and clinical applications, Br J Clin Pharmacol, 52, pp. 631-646, (2001)
[3]  
Maskell NA, Cooke S, Meecham Jones DJ, Prior JG, Butland RJ, The use of automated strain gauge plethysmography in the diagnosis of deep vein thrombosis, Br J Radiol, 75, pp. 648-651, (2002)
[4]  
Sax FL, Cannon RO, Hanson C, Epstein SE, Impaired forearm vasodilator reserve in patients with microvascular angina. Evidence of a generalized disorder of vascular function?, N Engl J Med, 317, pp. 1366-1370, (1987)
[5]  
Owen-Reece H, Smith M, Elwell CE, Goldstone JC, Near infrared spectroscopy, Br J Anaesth, 82, pp. 418-426, (1999)
[6]  
Edmonds HL, Multi-modality neurophysiologic monitoring for cardiac surgery, Heart Surg Forum, 5, pp. 225-228, (2002)
[7]  
Nakayama M, Iwasaki S, Ichinose H, Yamamoto S, Kanaya N, Namiki A, Intraoperative acute lower extremity ischemia detected by near-infrared spectroscopy, J Cardiothorac Vasc Anesth, 15, pp. 624-625, (2001)
[8]  
Akca O, Doufas AG, Morioka N, Iscoe S, Fisher J, Sessler DI, Hypercapnia improves tissue oxygenation, Anesthesiology, 97, pp. 801-806, (2002)
[9]  
Harel F, Dupuis J, Benelfassi A, Ruel N, Gregoire J, Radionuclide plethysmography for noninvasive evaluation of peripheral arterial blood flow, Am J Physiol Heart Circ Physiol, 289, pp. H258-H262, (2005)
[10]  
Saha GB, Fundamentals of nuclear pharmacy, (1998)