Isolated meningeal chloroma (granulocytic sarcoma) – a case report and review of the literature

被引:0
作者
C. Binder
M. Tiemann
D. Haase
A. Humpe
M. Kneba
机构
[1] Department of Hematology and Oncology,
[2] Georg-August University,undefined
[3] Robert-Koch-Str. 40,undefined
[4] D-37075 Göttingen,undefined
[5] Germany e-mail: cbinder@med.uni-goettingen.de Fax: +49-551-392914,undefined
[6] Institute of Hematopathology,undefined
[7] Christian-Albrecht-University,undefined
[8] Kiel,undefined
[9] Germany,undefined
[10] 2nd Medical Clinic,undefined
[11] Christian-Albrecht-University,undefined
[12] Kiel,undefined
[13] Germany,undefined
来源
Annals of Hematology | 2000年 / 79卷
关键词
Key words Chloroma; Acute myeloblastic leukemia; Chemotherapy; Autologous stem cell transplantation;
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摘要
Isolated chloromas (granulocytic sarcomas) are rare tumors, most of them progressing to acute myeloblastic leukemia within months. There are still no conclusive treatment strategies for this entity; however, early antileukemic chemotherapy seems to lower the probability of developing systemic disease and prolong survival. We report on a patient with isolated meningeal chloroma, primarily misdiagnosed as a high-grade Non-Hodgkin's lymphoma. Two cycles of antileukemic induction chemotherapy were administered, followed by local irradiation and intensified consolidation therapy with autologous stem cell transplantation. After 20 months, he is still in complete remission.
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页码:459 / 462
页数:3
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