Microstaging of Breast Cancer Patients Using Cytokeratin Staining of the Sentinel Lymph Node

被引:0
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作者
Robert H. Schreiber
Solange Pendas
Ni Ni Ku
Douglas S. Reintgen
Alan R. Shons
Claudia Berman
David Boulware
Charles E. Cox
机构
[1] Departments of Surgery,Departments of Radiology
[2] Departments of Pathology,Biostatistics Core
[3] University of South Florida,Department of Surgery
[4] H. Lee Moffitt Cancer Center,Comprehensive Breast Cancer Program
[5] Maimonides Medical Center,undefined
[6] H. Lee Moffitt Cancer Center and Research Institute,undefined
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关键词
Breast cancer; Cytokeratin; Microstaging; Sentinel lymph nodes;
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摘要
Background: Sentinel lymph node (SLN) mapping is an effective and accurate method of axillary nodal evaluation for metastatic disease. Cytokeratin (CK) immunohistochemical (IHC) staining of the SLN has found micrometastatic disease previously undetected by routine hematoxylin and eosin (H&E) stains. The purpose of this study is to determine the number of patients who were upstaged or microstaged, i.e., detected to have micrometastatic disease only by combined lymphatic mapping with CK IHC.
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页码:95 / 101
页数:6
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