Association of tyrosine hydroxylase 01 (TH01) microsatellite and insulin gene (INS) variable number of tandem repeat (VNTR) with type 2 diabetes and fasting insulin secretion in Mexican population

被引:0
作者
J. Berumen
L. Orozco
H. Gallardo-Rincón
E. Juárez-Torres
E. Barrera
M. Cruz-López
R. E. Benuto
E. Ramos-Martinez
M. Marin-Madina
A. Alvarado-Silva
A. Valladares-Salgado
J. J. Peralta-Romero
H. García-Ortiz
L. A. Martinez-Juarez
A. Montoya
D. A. Alvarez-Hernández
J. Alegre-Diaz
P. Kuri-Morales
R. Tapia-Conyer
机构
[1] Unidad de Investigación en Medicina Experimental,Facultad de Medicina
[2] Universidad Nacional Autónoma de México,Laboratorio de Inmunogenómica y Enfermedades Metabólicas
[3] Instituto Nacional de Medicina Genómica,Departamento de Soluciones Operativas
[4] Secretaria de Salud,Laboratorio Huella Génica
[5] Fundación Carlos Slim,Unidad de Investigación Médica en Bioquímica, Hospital de Especialidades
[6] Centro Universitario de Ciencias de la Salud,Center for Humanitarian Health
[7] Universidad de Guadalajara,Facultad de Medicina
[8] Unidad de Diabetes,Proyecto OriGen
[9] Centro Médico Nacional Siglo XXI,undefined
[10] Instituto Mexicano del Seguro Social,undefined
[11] Johns Hopkins Bloomberg School of Public Health,undefined
[12] Universidad Nacional Autónoma de México,undefined
[13] Instituto Tecnologico y de Estudios Superiores de Monterrey,undefined
来源
Journal of Endocrinological Investigation | 2024年 / 47卷
关键词
Diabetes; Insulin; rs689;
D O I
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摘要
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页码:571 / 583
页数:12
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  • [1] Bennett ST(1995)Susceptibility to human type 1 diabetes at IDDM2 is determined by tandem repeat variation at the insulin gene minisatellite locus Nat Genet 9 284-292
  • [2] Lucassen AM(1997)The insulin gene is transcribed in the human thymus and transcription levels correlated with allelic variation at the INS VNTR-IDDM2 susceptibility locus for type 1 diabetes Nat Genet 15 293-297
  • [3] Gough SCL(2000)Influence of allele lineage on the role of the insulin minisatellite in susceptibility to type 1 diabetes Hum Mol Genet 9 2929-2935
  • [4] Pugliese A(2013)Insulin-like growth factor 1 gene (CA)n repeats and a variable number of tandem repeats of the insulin gene in Brazilian children born small for gestational age Clinics (Sao Paulo) 68 785-791
  • [5] Zeller M(1988)Polymorphism at the 5' end flanking region of the insulin gene is associated with reduced insulin secretion in healthy individuals Eur J Clin Invest 18 582-586
  • [6] Fernandez A(1995)The minisatellite in the diabetes susceptibility locus IDDM2 regulates insulin transcription Nat Genet 9 293-298
  • [7] Stead JD(1999)INS VNTR allelic variation and dynamic insulin secretion in healthy adult non-diabetic Caucasian subjects Diabet Med 16 910-917
  • [8] Buard J(1995)Regulation of insulin gene expression by the IDDM associated, insulin locus haplotype Hum Mol Genet 4 501-506
  • [9] Todd JA(1996)Imprinted and genotype-specific expression of genes at the IDDM2 locus in pancreas and leucocytes J Autoimmun 9 397-403
  • [10] Jeffreys AJ(1984)Polymorphism in the 5' flanking region of the human insulin gene. Relationships with noninsulin-dependent diabetes mellitus, glucose and insulin concentrations, and diabetes treatment in the Pima Indians J Clin Invest 74 2129-2135