A Physiologically Based Pharmacokinetic Model of Amiodarone and its Metabolite Desethylamiodarone in Rats: Pooled Analysis of Published Data

被引:0
作者
Jing-Tao Lu
Ying Cai
Feng Chen
Wei-Wei Jia
Zhe-Yi Hu
Yuan-Sheng Zhao
机构
[1] Michigan State University,Department of Biochemistry and Molecular Biology
[2] Michigan State University,Department of Physiology
[3] School of Pharmacy,Department of Clinical Pharmacy
[4] Hainan Medical University,Department of Pharmacology and Systems Therapeutics
[5] Graduate School,undefined
[6] Tianjin University of Traditional Chinese Medicine,undefined
[7] College of Pharmacy,undefined
[8] University of Tennessee Health Science Center,undefined
[9] Mount Sinai School of Medicine,undefined
来源
European Journal of Drug Metabolism and Pharmacokinetics | 2016年 / 41卷
关键词
Amiodarone; PBPK Model; Tissue Compartment; Pool Dataset; Desethylamiodarone;
D O I
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中图分类号
学科分类号
摘要
引用
收藏
页码:689 / 703
页数:14
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