Functional promoter upstream p53 regulatory sequence of IGFBP3 that is silenced by tumor specific methylation

被引:0
作者
Tadashi Hanafusa
Toshiyuki Shinji
Hidenori Shiraha
Kazuhiro Nouso
Yoshiaki Iwasaki
Eichiro Yumoto
Toshiro Ono
Norio Koide
机构
[1] Okayama University Advanced Science Research Center,Department of Radiation Research, Shikata Laboratory
[2] Okayama University Graduate School of Medicine and Dentistry,Department of Laboratory Medicine
[3] Okayama University Graduate School of Medicine and Dentistry,First Department of Internal Medicine
[4] Albert Einstein College of Medicine,Department of Microbiology and Immunology
来源
BMC Cancer | / 5卷
关键词
HepG2 Cell; Promoter Hypermethylation; Electrophoresis Mobility Shift Assay; Cancer Profile Array; Human Hepatoblastoma Cell Line HepG2;
D O I
暂无
中图分类号
学科分类号
摘要
引用
收藏
相关论文
共 174 条
[1]  
Clemmons DR(1997)Insulin-like growth factor binding proteins and their role in controlling IGF actions Cytokine Growth Factor Rev 8 45-62
[2]  
Lee KW(2002)Nuclear effects: unexpected intracellular actions of insulin-like growth factor binding protein-3 J Endocrinol 175 33-40
[3]  
Cohen P(1995)Induction of the growth inhibitor IGF-binding protein 3 by p53 Nature 377 646-649
[4]  
Buckbinder L(1996)Insulin-like growth factor binding protein 3 mediates retinoic acid- and transforming growth factor beta2-induced growth inhibition in human breast cancer cells Cancer Res 56 1545-1550
[5]  
Talbott R(1997)Insulin-like growth factor (IGF)-binding protein-3 induces apoptosis and mediates the effects of transforming growth factor-beta1 on programmed cell death through a p53- and IGF-independent mechanism J Biol Chem 272 12181-12188
[6]  
Velasco-Miguel S(1996)Tumor necrosis factor alpha stimulates insulin-like growth factor binding protein 3 expression in cultured porcine Sertoli cells Endocrinology 137 296-303
[7]  
Takenaka I(2002)Insulin-like Growth Factor (IGF)-binding Protein-3 Mutants That Do Not Bind IGF-I or IGF-II Stimulate Apoptosis in Human Prostate Cancer Cells J Biol Chem 277 10489-10497
[8]  
Faha B(1999)Down-regulation of insulin-like growth factor binding proteins and growth modulation in hepatoma cells by retinoic acid Hepatology 29 1091-1098
[9]  
Seizinger BR(2002)A possible role for insulin-like growth factor-binding protein-3 autocrine/paracrine loops in controlling hepatocellular carcinoma cell proliferation Cell Growth Differ 13 115-122
[10]  
Kley N(2000)Cell-specific localization of insulin-like growth factor binding protein mRNAs in rat liver Am J Physiol Gastrointest Liver Physiol 278 G447-57