Chemical constituents from the leaves of Juglans mandshurica

被引：0
作者：
Da Lei Yao
Chang Hao Zhang
Jie Luo
Mei Jin
Ming Shan Zheng
Jiong Mo Cui
Jong Keun Son
Gao Li
机构：
[1] Yanbian University College of Pharmacy,Key Laboratory of Natural Resources of the Changbai Mountain and Functional Molecules, Ministry of Education
[2] Yanbian University Hospital,College of Pharmacy
[3] Yeungnam University,undefined
来源：
Archives of Pharmacal Research | 2015年 / 38卷
关键词：
Juglandaceae; Diarylheptanoid; Cytotoxicity; Tetralone; Phenylpropanoid;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Two new (1 and 3) and two known diarylheptanoids (2 and 4), along with two tetralones (5 and 6), one naphthoquinone (7), four phenylpropanoids (8–11), and one phenol (12) were isolated from the leaves of Juglans mandshurica. Their structures were elucidated on the basis of spectral and chemical data. Compounds 2 and 10 are firstly isolated from this plant and 8 and 12 were isolated from the Juglans genus for the first time. Among these compounds, only 7 exhibited moderate cytotoxicities against cultured MGC-803, A549, K562, and HeLa tumor cell lines with IC50 values of 25.90, 28.60, 39.06, 44.90 μM, respectively.
引用
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页码：480 / 484
页数：4
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