Cracking the BAFF code

被引：0
|
作者：
Fabienne Mackay
Pascal Schneider
机构：
[1] Faculty of Medicine,Department of Immunology
[2] Nursing and Health Sciences,undefined
[3] Monash University,undefined
[4] Alfred Hospital,undefined
来源：
Nature Reviews Immunology | 2009年 / 9卷
关键词：
D O I：
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中图分类号：
学科分类号：
摘要：
Studies showing how BAFF and its closely related homologue APRIL activate their receptors and transmit growth and survival signals to B cells have shed new light on the association between BAFF and autoimmunity. This knowledge has prompted several clinical trials testing BAFF and APRIL antagonists for the treatment of autoimmune diseases and lymphomas.
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页码：491 / 502
页数：11
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