Type I interferons: crucial participants in disease amplification in autoimmunity

被引：0
|
作者：
John C. Hall
Antony Rosen
机构：
[1] Johns Hopkins University School of Medicine,Division of Rheumatology, Department of Medicine
[2] 5200 Eastern Avenue,undefined
[3] Mason F. Lord Building,undefined
[4] Center Tower,undefined
来源：
Nature Reviews Rheumatology | 2010年 / 6卷
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摘要：
Mounting evidence indicates a role for interferons in the pathogenesis of systemic autoimmunity. This Review focuses on the role of the type I interferon pathway in the development of systemic autoimmune diseases, describing the mechanisms by which these cytokines are produced and how they exert their effects in both the normal antiviral immune response and in autoimmune disease.
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页码：40 / 49
页数：9
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