The pharmacologic treatment of short bowel syndrome: new tricks and novel agents

被引：16
作者：
Bechtold M.L. [1 ]
McClave S.A. [1 ]
Palmer L.B. [1 ]
Nguyen D.L. [1 ]
Urben L.M. [1 ]
Martindale R.G. [1 ]
Hurt R.T. [1 ]
机构：
[1] Departments of Medicine, University of Missouri, Columbia, MO
来源：
Current Gastroenterology Reports | 2014年 / 16卷 / 7期
关键词：
Small bowel syndrome; Pharmacology; Malabsorption; Treatment; Review;
D O I：
10.1007/s11894-014-0392-2
中图分类号：
学科分类号：
摘要：
Short bowel syndrome (SBS) is a manifestation of massive resection of the intestines resulting in severe fluid, electrolyte, and vitamin/mineral deficiencies. Diet and parenteral nutrition play a large role in the management of SBS; however, pharmacologic options are becoming more readily available. These pharmacologic agents focus on reducing secretions and stimulating intestinal adaptation. The choice of medication is highly dependent on the patient's symptoms, remaining anatomy, and risk versus benefit profile for each agent. This article focuses on common and novel pharmacologic medications used in SBS, including expert advice on their indications and use.
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