Cardiovascular risks of androgen deprivation therapy for prostate cancer

被引：1

作者：

Miller, K. ^{[1
]}

机构：

[1] Klin & Hsch Ambulanz Urol, Charitepl 1, D-10117 Berlin, Germany

来源：

UROLOGE | 2016年 / 55卷 / 05期

关键词：

Prostate cancer; Androgen deprivation therapy; Cardio vascular events; GnRH antagonists; LHRH agonists; MEN; DISEASE; ASSOCIATION; SUPPRESSION; MORBIDITY; MORTALITY;

D O I：

10.1007/s00120-015-0021-1

中图分类号：

R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];

学科分类号：

1002 ; 100201 ;

摘要：

Androgen deprivation therapy (ADT) is the standard treatment for metastatic prostate cancer. It has increasingly been used in other stages of the disease as well. Besides well-known side effects caused by the lack of testosterone (impotency, osteoporosis, fatigue, loss of muscle mass), an increase of cardiovascular (CV) morbidity and mortality has recently been discussed in association with ADT. Cardiovascular side effects cannot be sufficiently explained by low testosterone levels. This review gives an overview of the recent literature, interprets the results, and offers clinical consequences.

引用

页码：627 / 631

页数：5

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