Src family kinases activity is required for transmitting purinergic P2X7 receptor signaling in cortical spreading depression and neuroinflammation

被引:0
作者
Lingdi Nie
Dongqing Ma
John P. Quinn
Minyan Wang
机构
[1] Centre for Neuroscience,Department of Biological Sciences
[2] Xi’an Jiaotong-Liverpool University (XJTLU),Department of Pharmacology and Therapeutics
[3] Institute of Systems,undefined
[4] Molecular and Integrative Biology,undefined
来源
The Journal of Headache and Pain | 2021年 / 22卷
关键词
Migraine; cortical spreading depression; P2X7 receptor; Src family kinases; glutamatergic pathway; neuroinflammation;
D O I
暂无
中图分类号
学科分类号
摘要
• SFKs activity-mediated P2X7 receptor signaling facilitates CSD propagation via glutamatergic pathway and also promotes neuroinflammation.
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