Cradle-to-gate life cycle assessment of a liquid pharmaceutical product through analysis of chemical production pathways

[1] Alfonsi K(2008)Green chemistry tools to influence a medicinal chemistry and research chemistry based organisation Green Chem 10 31-36

[2] Colberg J(2017)Comparative life cycle assessment of the use of an ionic liquid ([Bmim] Br) versus a volatile organic solvent in the production of acetylsalicylic acid J Clean Prod 168 1614-1624

[3] Dunn PJ(2014)Guidelines based on life cycle assessment for solvent selection during the process design and evaluation of treatment alternatives Green Chem 16 3045-3063

[4] Fevig T(2007)Repeating history: pharmaceuticals in the environment Environ Sci Technol 41 8211-8217

[5] Jennings S(2018)Physical and chemical assessment of 1, 3 Propanediol as a potential substitute of propylene glycol in refill liquid for electronic cigarettes Sci Rep 8 1-10

[6] Johnson TA(2014)Combined simulation–optimization methodology to reduce the environmental impact of pharmaceutical processes: application to the production of Penicillin V J Clean Prod 76 55-63

[7] Stefaniak M(2015)Life cycle inventory improvement in the pharmaceutical sector: assessment of the sustainability combining PMI and LCA tools Green Chem 17 3390-3400

[8] Alviz PLA(1999)Pharmaceuticals and personal care products in the environment: Agents of subtle change? Environ Health Perspect 107 907-938

[9] Alvarez AJ(2017)The potential ecotoxicological impact of pharmaceutical and personal care products on humans and freshwater, based on USEtox™ characterization factors. A Spanish case study of toxicity impact scores Sci Total Environ 609 429-445

[10] Amelio A(2013)Exergetic sustainability assessment of batch versus continuous wet granulation based pharmaceutical tablet manufacturing: a cohesive analysis at three different levels Green Chem 15 3039-3048

[1] Alfonsi K(2008)Green chemistry tools to influence a medicinal chemistry and research chemistry based organisation Green Chem 10 31-36

[2] Colberg J(2017)Comparative life cycle assessment of the use of an ionic liquid ([Bmim] Br) versus a volatile organic solvent in the production of acetylsalicylic acid J Clean Prod 168 1614-1624

[3] Dunn PJ(2014)Guidelines based on life cycle assessment for solvent selection during the process design and evaluation of treatment alternatives Green Chem 16 3045-3063

[4] Fevig T(2007)Repeating history: pharmaceuticals in the environment Environ Sci Technol 41 8211-8217

[5] Jennings S(2018)Physical and chemical assessment of 1, 3 Propanediol as a potential substitute of propylene glycol in refill liquid for electronic cigarettes Sci Rep 8 1-10

[6] Johnson TA(2014)Combined simulation–optimization methodology to reduce the environmental impact of pharmaceutical processes: application to the production of Penicillin V J Clean Prod 76 55-63

[7] Stefaniak M(2015)Life cycle inventory improvement in the pharmaceutical sector: assessment of the sustainability combining PMI and LCA tools Green Chem 17 3390-3400

[8] Alviz PLA(1999)Pharmaceuticals and personal care products in the environment: Agents of subtle change? Environ Health Perspect 107 907-938

[9] Alvarez AJ(2017)The potential ecotoxicological impact of pharmaceutical and personal care products on humans and freshwater, based on USEtox™ characterization factors. A Spanish case study of toxicity impact scores Sci Total Environ 609 429-445

[10] Amelio A(2013)Exergetic sustainability assessment of batch versus continuous wet granulation based pharmaceutical tablet manufacturing: a cohesive analysis at three different levels Green Chem 15 3039-3048