CNS Regulation of Glucose Homeostasis: Role of the Leptin-Melanocortin System

[1] Kamohara S(1997)Acute stimulation of glucose metabolism in mice by leptin treatment Nature. 389 374-377

[2] Burcelin R(1999)Leptin restores euglycemia and normalizes glucose turnover in insulin-deficient diabetes in the rat Diabetes. 48 1487-1492

[3] Halaas JL(2016)The long road to leptin J Clin Invest 126 4727-4734

[4] Friedman JM(1994)Positional cloning of the mouse obese gene and its human homologue Nature. 372 425-432

[5] Charron MJ(1995)Effects of the obese gene product on body weight regulation in Ob/Ob mice Science. 269 540-543

[6] Chinookoswong N(1997)Leptin selectively decreases visceral adiposity and enhances insulin action J Clin Invest 100 3105-3110

[7] Wang JL(1999)Chronic leptin administration increases insulin-stimulated skeletal muscle glucose uptake and transport Metabolism. 48 671-676

[8] Shi ZQ(2001)Leptin administration improves skeletal muscle insulin responsiveness in diet-induced insulin-resistant rats Am J Physiol Endocrinol Metab 280 E130-E142

[9] Friedman J(2002)Central leptin increases insulin sensitivity in streptozotocin-induced diabetic rats Am J Physiol Endocrinol Metab 282 E1084-E1091

[10] Zhang Y(1998)Chronic leptin infusion increases arterial pressure Hypertension. 31 409-414

[1] Kamohara S(1997)Acute stimulation of glucose metabolism in mice by leptin treatment Nature. 389 374-377

[2] Burcelin R(1999)Leptin restores euglycemia and normalizes glucose turnover in insulin-deficient diabetes in the rat Diabetes. 48 1487-1492

[3] Halaas JL(2016)The long road to leptin J Clin Invest 126 4727-4734

[4] Friedman JM(1994)Positional cloning of the mouse obese gene and its human homologue Nature. 372 425-432

[5] Charron MJ(1995)Effects of the obese gene product on body weight regulation in Ob/Ob mice Science. 269 540-543

[6] Chinookoswong N(1997)Leptin selectively decreases visceral adiposity and enhances insulin action J Clin Invest 100 3105-3110

[7] Wang JL(1999)Chronic leptin administration increases insulin-stimulated skeletal muscle glucose uptake and transport Metabolism. 48 671-676

[8] Shi ZQ(2001)Leptin administration improves skeletal muscle insulin responsiveness in diet-induced insulin-resistant rats Am J Physiol Endocrinol Metab 280 E130-E142

[9] Friedman J(2002)Central leptin increases insulin sensitivity in streptozotocin-induced diabetic rats Am J Physiol Endocrinol Metab 282 E1084-E1091

[10] Zhang Y(1998)Chronic leptin infusion increases arterial pressure Hypertension. 31 409-414