Fertilization Potential of Human Sperm Is Correlated with Endogenous Platelet-Activating Factor Content

被引：0
作者：
Andrew A. Toledo
Dorothy Mitchell-Leef
Carlene W. Elsner
Scott M. Slayden
William E. Roudebush
机构：
[1] Reproductive Biology Associates,
来源：
Journal of Assisted Reproduction and Genetics | 2003年 / 20卷
关键词：
Fertilization potential; human sperm; platelet-activating factor; SPA;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Purpose: Platelet-activating factor (PAF) is a potent signaling phospholipid that is found in mammalian sperm and has a positive correlation with fertility. Whereas PAF is present in human sperm, there are no relational reports on its content and the cells fertilization potential. Therefore, the study objective was to determine if PAF content in capacitated-induced sperm is related to fertilization potential as determined by the sperm penetration assay (SPA).
引用
收藏
页码：192 / 195
页数：3
相关论文
共 62 条
  • [1] YanagimachiR BS(1976)The use of zona-free animal ova as a test-system for the assessment of the fertilizing capacity of human sperm Biol Reprod 15 471-476
  • [2] YanagimachiH undefined(2002)A review of the effect of platelet-activating factor on male reproduction and sperm function J Androl 23 471-476
  • [3] RogersBJ undefined(1989)Platelet-activating factor: A paracrine factor in preimplantation stages of development? Biol Reprod 40 907-913
  • [4] LevineAS undefined(1991)The presence of platelet activating factor-like activity in human sperm Fertil Steril 55 372-376
  • [5] KortHI undefined(2000)Platelet-activating factor content in human spermatozoa and pregnancy outcome Fertil Steril 74 257-260
  • [6] ToledoAA undefined(1959)A rapid method of total lipid extraction and purification Can J Biochem Physiol 37 911-917
  • [7] RoudebushWE undefined(1992)Platelet-activating factor acetylhydrolase in seminal plasma Fert Steril 57 193-198
  • [8] HarperMJK undefined(1987)Enzymatic deacetylation and acetylation of ether phospholipids related to platelet-activating factor in human semen with short and long liquefaction times Ann NY Acad Sci 513 583-585
  • [9] MinhasBS undefined(1990)Role of spermatozoal platelet-activating factor in fertilization Prostaglandins 39 61-74
  • [10] KumarR undefined(1991)Platelet-activating factor stimulates motion parameters of cryopreserved human sperm Fertil Steril 56 768-770
1234567