Acute coronary syndromes in patients with diabetes mellitus: Diagnosis, prognosis, and current management strategies

被引:2
作者
Rhoda Brosnan
L. Kristin Newby
机构
[1] Duke Clinical Research Institute, Durham, NC 27715-7969
关键词
Diabetic Patient; Acute Coronary Syndrome; Abciximab; Tirofiban; Nondiabetic Patient;
D O I
10.1007/s11886-003-0066-4
中图分类号
学科分类号
摘要
The incidence of type-2 diabetes mellitus is rising rapidly both in the United States and worldwide. Because of its presence in so many patients with acute coronary syndromes, it is becoming essential for cardiologists to understand the basic pathophysiology of insulin resistance, its role in the development of type-2 diabetes, and its association with accelerated atherosclerosis. Because diabetes imparts a worse prognosis among patients with acute coronary syndromes, these patients warrant aggressive antiplatelet and antithrombotic therapy, as well as a more invasive management strategy. Copyright © 2003 by Current Science Inc.
引用
收藏
页码:296 / 302
页数:6
相关论文
共 28 条
[1]  
Harris M.I., Flegal K.M., Conie C.C., Et al., Prevalence of diabetes, impaired fasting glucose and impaired glucose tolerance in US adults: The third national health and nutrition examination survey 1988-1994, Diabetes Care, 21, pp. 518-524, (1998)
[2]  
Garcia M.J., McNamara P.M., Gordon T., Et al., Morbidity and mortality in diabetics in the Framingham population. Sixteen-year follow-up study, Diabetes, 23, pp. 105-111, (1974)
[3]  
Haffner S.M., Sehto S., Ronnemaa T., Et al., Mortality from coronary heart disease in subjects with type 2 diabetes and in nondiabetic subjects with and without prior myocardial infarction, N. Engl. J. Med., 339, pp. 229-234, (1998)
[4]  
Abbott R.D., Donague R.P., Kannel W.B., Et al., The impact of diabetes on survival following myocardial infarction in men vs women. The Framingham Study, JAMA, 260, pp. 3456-3460, (1988)
[5]  
McGuire D.K., Emanuelsson H., Granger C.B., Et al., Influence of diabetes mellitus on clinical outcomes across the spectrum of acute coronary syndromes. Findings of the GUSTO-IIb study, Eur. Heart J., 21, pp. 1750-1758, (2001)
[6]  
Report of the Expert Committee on the Diagnosis and Classification of Diabetes Mellitus, Diabetes Care, 23, SUPPL. 1, (2000)
[7]  
Ginsberg H.N., Insulin resistance and cardiovascular disease, J. Clin. Invest., 106, pp. 453-458, (2000)
[8]  
Beckman J.A., Creager M.A., Libby P., Diabetes and atherosclerosis: Epidemiology, pathophysiology and management, JAMA, 287, pp. 2570-2581, (2002)
[9]  
Aronson D., Bloomgarden Z., Rayfield E.J., Potential mechanisms promoting restenosis in diabetic patients, J. Am. Coll. Cardiol., 27, pp. 528-535, (1996)
[10]  
Bonow R.O., Mitch W.E., Nesto R.W., Et al., Diabetes and cardiovascular disease: Management of cardiovascular-renal complications, Circulation, 105, (2002)