Biosynthesis of biocompatible cadmium telluride quantum dots using yeast cells

被引：0
作者：
Haifeng Bao
Na Hao
Yunxia Yang
Dongyuan Zhao
机构：
[1] Monash University,Department of Chemical Engineering
来源：
Nano Research | 2010年 / 3卷
关键词：
Cadmium telluride (CdTe) quantum dots; biosynthesis; biocompatible; bio-imaging;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
We demonstrate a simple and efficient biosynthesis method to prepare easily harvested biocompatible cadmium telluride (CdTe) quantum dots (QDs) with tunable fluorescence emission using yeast cells. Ultraviolet-visible (UV-vis) spectroscopy, photoluminescence (PL) spectroscopy, X-ray diffraction (XRD), and transmission electron microscopy (TEM) confirm that the CdTe QDs are formed via an extracellular growth and subsequent endocytosis pathway and have size-tunable optical properties with fluorescence emission from 490 to 560 nm and a cubic zinc blende structure with good crystallinity. In particular, the CdTe QDs with uniform size (2-3.6 nm) are protein-capped, which makes them highly soluble in water, and in situ bio-imaging in yeast cells indicates that the biosynthesized QDs have good biocompatibility. This work provides an economic and environmentally friendly approach to synthesize highly fluorescent biocompatible CdTe QDs for bio-imaging and bio-labeling applications.[media not available: see fulltext]
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页码：481 / 489
页数：8
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[21]  
Rogach A. L.(2002)Enzyme mediated extracellular synthesis of CdS nanoparticles by the fungus, J. Am. Chem. Soc. 124 12108-588
[22]  
Bruchez M.(2002)Microbial synthesis of semiconductor CdS nanoparticles, their characterization, and their use in the fabrication of an ideal diode Biotechnol. Bioeng. 78 583-818
[23]  
Moronne M.(2002)Microbial synthesis of semiconductor PbS nanocrystallites Adv. Mater. 14 815-1139
[24]  
Gin P.(2006)Biological synthesis of semiconductor zinc sulfide nanoparticles by immobilized Rhodobacter sphaeroides Biotechnol. Lett. 28 1135-1559
[25]  
Weiss S.(2004)Bacterial biosynthesis of cadmium sulfide nanocrystals Chem. Biol. 11 1553-5189
[26]  
Alivisatos A. P.(2008)Microbial synthesis of CdS nanocrystals in genetically engineered Angew. Chem. Int. Ed. 47 5186-2364
[27]  
Chan W. C. W.(2009)Living yeast cells as a controllable biosynthesizer for fluorescent quantum dots Adv. Funct. Mater. 19 2359-8363
[28]  
Nie S. M.(1998)Strongly photoluminescent CdTe nanocrystals by proper surface modification J. Phys. Chem. B 102 8360-2860
[29]  
Mamedova N. N.(2003)Experimental determination of the extinction coefficient of CdTe, CdSe, and CdS nanocrystals Chem. Mater. 15 2854-7185
[30]  
Kotov N. A.(2002)Thiol-capping of CdTe nanocrystals: An alternative to organometallic synthetic routes J. Phys. Chem. B 106 7177-8474
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