Sickle Cell Anemia with Malaria: A Rare Case Report

被引:0
作者
Narendra Kumar Gupta
Meenakshi Gupta
机构
[1] ESIC Model Hospital,Department of Pathology
[2] Gupta Pathology and Sonography Centre,undefined
来源
Indian Journal of Hematology and Blood Transfusion | 2014年 / 30卷
关键词
Sickle cell disease; Malaria;
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学科分类号
摘要
Sickle cell disease is the prototype of hereditary hemoglobinopathies, characterized by the production of structurally abnormal hemoglobin. Sickle cell anemia results from a point mutation that leads to substitution of valine for glutamic acid at the sixth position of the β globin chain. We report a young male admitted with fever and weakness for 3 days. Hematological test reveals Plasmodium falciparum malaria parasite and sickle cell anemia. Patient was treated and get cured from malaria and discharged.
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页码:38 / 40
页数:2
相关论文
共 49 条
[1]  
Lehman H(1952)Sickle cell trait in southern India Br Med J 1 404-405
[2]  
Cutbush M(2002)Sickle cell disease in India Curr Opin Hematol 9 117-122
[3]  
Mohanty D(1964)Polymorphism and natural selection in human populations Cold Spring Harb Symp Quant Biol 24 137-149
[4]  
Mukherjee MB(1983)A case–control study in northern Liberia of Ann Trop Med Parasitol 77 239-246
[5]  
Allison AC(1991) malaria in haemoglobin Nature 352 595-600
[6]  
Willcox M(2002) and beta-thalassaemia traits Lancet 359 1311-1312
[7]  
Bjorkman A(1978)Common west African HLA antigens are associated with protection from severe malaria Proc Natl Acad Sci USA 75 1994-1997
[8]  
Brohult J(1978)Protective effects of the sickle cell gene against malaria morbidity and mortality Nature 274 701-703
[9]  
Pehrson PO(1970)Erythrocytic mechanism of sickle cell resistance to malaria Lancet 1 319-321
[10]  
Rombo L(1978)Cellular mechanism for the protective effect of haemoglobin Science 202 650-652