NOTCH gene alterations in metastatic colorectal cancer in the Nationwide Cancer Genome Screening Project in Japan (SCRUM-Japan GI-SCREEN)

被引:0
作者
Takeshi Kajiwara
Tomohiro Nishina
Akio Nakasya
Natsumi Yamashita
Riu Yamashita
Yoshiaki Nakamura
Manabu Shiozawa
Satoshi Yuki
Hiroya Taniguchi
Hiroki Hara
Takashi Ohta
Taito Esaki
Eiji Shinozaki
Atsuo Takashima
Toshikazu Moriwaki
Tadamichi Denda
Koushiro Ohtsubo
Yu Sunakawa
Yosuke Horita
Hisato Kawakami
Takeshi Kato
Taroh Satoh
Koji Ando
Tomonori Mizutani
Hisateru Yasui
Masahiro Goto
Hiroyuki Okuyama
Kentaro Yamazaki
Takayuki Yoshino
Ichinosuke Hyodo
机构
[1] National Hospital Organization Shikoku Cancer Center,Department of Gastrointestinal Medical Oncology
[2] National Hospital Organization Shikoku Cancer Center,Clinical Research Center
[3] National Cancer Center,Division of Translational Informatics, Exploratory Oncology Research and Clinical Trial Center
[4] National Cancer Center Hospital East,Department of Gastroenterology and Gastrointestinal Oncology
[5] Kanagawa Cancer Center,Department of Gastrointestinal Surgery
[6] Hokkaido University Hospital,Department of Gastroenterology and Hepatology
[7] Aichi Cancer Center Hospital,Department of Clinical Oncology
[8] Saitama Cancer Center,Department of Gastroenterology
[9] Kansai Rosai Hospital,Department of Clinical Oncology
[10] National Hospital Organization Kyushu Cancer Center,Department of Gastrointestinal and Medical Oncology
[11] Cancer Institute Hospital of Japanese Foundation for Cancer Research,Department of Gastroenterological Chemotherapy
[12] National Cancer Center Hospital,Department of Gastrointestinal Medical Oncology
[13] University of Tsukuba,Department of Gastroenterology, Faculty of Medicine
[14] Chiba Cancer Center,Division of Gastroenterology
[15] Kanazawa University,Division of Medical Oncology, Cancer Research Institute
[16] St. Marianna University School of Medicine,Department of Clinical Oncology
[17] Saitama Medical University International Medical Center,Department of Medical Oncology
[18] Kindai University Faculty of Medicine,Department of Medical Oncology
[19] National Hospital Organization Osaka National Hospital,Department of Surgery
[20] Osaka University,Department of Frontier Science for Cancer and Chemotherapy, Graduate School of Medicine
[21] Kyushu University,Department of Surgery and Science, Graduate School of Medical Sciences
[22] Kyorin University Faculty of Medicine,Department of General Medicine, Department of Medical Oncology
[23] Kobe City Medical Center General Hospital,Department of Medical Oncology
[24] Osaka Medical and Pharmaceutical University,Cancer Chemotherapy Center
[25] Kagawa University Hospital,Department of Clinical Oncology
[26] Shizuoka Cancer Center,Division of Gastrointestinal Oncology
来源
Journal of Cancer Research and Clinical Oncology | 2022年 / 148卷
关键词
gene; Colorectal cancer; Next-generation sequencing; Prognosis;
D O I
暂无
中图分类号
学科分类号
摘要
引用
收藏
页码:2841 / 2854
页数:13
相关论文
共 99 条
[1]  
Arcaroli JJ(2016)A NOTCH1 gene copy number gain is a prognostic indicator of worse survival and a predictive biomarker to a Notch1 targeting antibody in colorectal cancer Int J Cancer 138 195-205
[2]  
Tai WM(2017)The varied roles of Notch in cancer Annu Rev Pathol 12 245-275
[3]  
McWilliams R(2012)Comprehensive molecular characterization of human colon and rectal cancer Nature 487 330-337
[4]  
Aster JC(2011)Notch1 and Notch2 have opposite prognostic effects on patients with colorectal cancer Ann Oncol 22 2440-2447
[5]  
Pear WS(2006)Jagged 1 is a beta-catenin target gene required for ectopic hair follicle formation in adult epidermis Development 133 4427-4438
[6]  
Blacklow SC(2017)Activating NOTCH1 mutations define a distinct subgroup of patients with adenoid cystic carcinoma who have poor prognosis, propensity to bone and liver metastasis, and potential responsiveness to Notch1 inhibitors J Clin Oncol 35 352-360
[7]  
Chu D(2018)A phase I dose-escalation and dose-expansion study of brontictuzumab in subjects with selected solid tumors Ann Oncol 29 1561-1568
[8]  
Zhang Z(2019)Epithelial NOTCH signaling rewires the tumor microenvironment of colorectal cancer to drive poor-prognosis subtypes and metastasis Cancer Cell 36 319-336.e7
[9]  
Zhou Y(2017)Deciphering the Fringe-mediated Notch code: identification of activating and inhibiting sites allowing discrimination between ligands Dev Cell 40 193-201
[10]  
Estrach S(2006)Comparative integromics on VEGF family members Int J Oncol 28 1585-1589