The long reach of noncoding RNAs

被引：0

作者：

Elena Sotillo

Andrei Thomas-Tikhonenko

机构：

[1] The Children's Hospital of Philadelphia and University of Pennsylvania,Elena Sotillo and Andrei Thomas

[2] Philadelphia,Tikhonenko are in the Division of Cancer Pathobiology, Department of Pathology & Laboratory Medicine

[3] Pennsylvania,undefined

[4] USA.,undefined

来源：

Nature Genetics | 2011年 / 43卷

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摘要：

Transcription of genomic loci containing protein-coding genes often yields not only cognate mRNAs but also assorted noncoding RNAs (ncRNAs), which typically map in the vicinity of transcription start sites. A new study shows that far from being random byproducts of gene expression, many long ncRNAs (lncRNAs) are synthesized in a coordinate fashion and control important cellular processes, such as survival in the face of DNA damage.

引用

页码：616 / 617

页数：1

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