Improved skeletal muscle oxidative enzyme activity and restoration of PGC-1α and PPARβ/δ gene expression upon rosiglitazone treatment in obese patients with type 2 diabetes mellitus

[1] Patti ME(2003)Coordinated reduction of genes of oxidative metabolism in humans with insulin resistance and diabetes: Potential role of PGC1 and NRF1 Proc Natl Acad Sci USA 100 8466-8471

[2] Butte AJ(2003)PGC-1alpha-responsive genes involved in oxidative phosphorylation are coordinately downregulated in human diabetes Nat Genet 34 267-273

[3] Crunkhorn S(2002)Dysfunction of mitochondria in human skeletal muscle in type 2 diabetes Diabetes 51 2944-2950

[4] Cusi K(2004)Impaired mitochondrial activity in the insulin-resistant offspring of patients with type 2 diabetes N Engl J Med 350 664-671

[5] Berria R(2003)Mitochondrial dysfunction in the elderly: possible role in insulin resistance Science 300 1140-1142

[6] Kashyap S(2002)Banting lecture 2001: dysregulation of fatty acid metabolism in the etiology of type 2 diabetes Diabetes 51 7-18

[7] Mootha VK(2003)Mitochondrial biogenesis and remodeling during adipogenesis and in response to the insulin sensitizer rosiglitazone Mol Cell Biol 23 1085-1094

[8] Lindgren CM(2004)Mitochondrial remodeling in adipose tissue associated with obesity and treatment with rosiglitazone J Clin Invest 114 1281-1289

[9] Eriksson KF(2005)Pioglitazone induces mitochondrial biogenesis in human subcutaneous adipose tissue Diabetes 54 1392-1399

[10] Subramanian A(1967)Diet, muscle glycogen and physical performance Acta Physiol Scand 71 140-150

[1] Patti ME(2003)Coordinated reduction of genes of oxidative metabolism in humans with insulin resistance and diabetes: Potential role of PGC1 and NRF1 Proc Natl Acad Sci USA 100 8466-8471

[2] Butte AJ(2003)PGC-1alpha-responsive genes involved in oxidative phosphorylation are coordinately downregulated in human diabetes Nat Genet 34 267-273

[3] Crunkhorn S(2002)Dysfunction of mitochondria in human skeletal muscle in type 2 diabetes Diabetes 51 2944-2950

[4] Cusi K(2004)Impaired mitochondrial activity in the insulin-resistant offspring of patients with type 2 diabetes N Engl J Med 350 664-671

[5] Berria R(2003)Mitochondrial dysfunction in the elderly: possible role in insulin resistance Science 300 1140-1142

[6] Kashyap S(2002)Banting lecture 2001: dysregulation of fatty acid metabolism in the etiology of type 2 diabetes Diabetes 51 7-18

[7] Mootha VK(2003)Mitochondrial biogenesis and remodeling during adipogenesis and in response to the insulin sensitizer rosiglitazone Mol Cell Biol 23 1085-1094

[8] Lindgren CM(2004)Mitochondrial remodeling in adipose tissue associated with obesity and treatment with rosiglitazone J Clin Invest 114 1281-1289

[9] Eriksson KF(2005)Pioglitazone induces mitochondrial biogenesis in human subcutaneous adipose tissue Diabetes 54 1392-1399

[10] Subramanian A(1967)Diet, muscle glycogen and physical performance Acta Physiol Scand 71 140-150