Assessment of three levels of folic acid on serum folate and plasma homocysteine: a randomised placebo-controlled double-blind dietary intervention trial

被引:0
作者
BJ Venn
JI Mann
SM Williams
LJ Riddell
A Chisholm
MJ Harper
W Aitken
JI Rossaak
机构
[1] University of Otago,Department of Human Nutrition
[2] University of Otago,Department of Preventive and Social Medicine
[3] University of Otago,Department of Medical and Surgical Sciences
来源
European Journal of Clinical Nutrition | 2002年 / 56卷
关键词
homocysteine; folic acid; dosage; fortification; dietary intervention;
D O I
暂无
中图分类号
学科分类号
摘要
Objective: To determine the minimum effective dose of folic acid required to appreciably increase serum folate and to produce a significant reduction in plasma total homocysteine (tHcy).
引用
收藏
页码:748 / 754
页数:6
相关论文
共 76 条
[1]  
Bowtell DDL(1999)Rapid isolation of eukaryotic DNA Annal. Biochem. 162 463-465
[2]  
Daly LE(1995)Folate levels and neural tube defects: implications for prevention JAMA 274 1698-1702
[3]  
Kirke PN(1999)Homocyst(e)ine and cardiovascular disease. A critical review of the epidemiologic evidence Ann. Intern. Med. 131 363-375
[4]  
Molloy A(1998)Estimation of individual intakes of folate in women of childbearing age with and without simulation of folic acid fortification J. Am. Diet. Assoc. 98 985-988
[5]  
Weir DG(1996)Results of an international round robin for serum and whole-blood folate Clin. Chem. 42 1689-1694
[6]  
Scott JM(1999)The effect of folic acid fortification on plasma folate and total homocysteine concentrations New Engl. J. Med. 340 1449-1454
[7]  
Eikelboom JW(1987)A rapid method for the purification of DNA from blood Nucleic Acids Res. 15 9611-916
[8]  
Lonn E(1999)Trends in serum folate after food fortification Lancet 354 915-362
[9]  
Genest J(1992)Plasma folate adequacy as determined by homocysteine level Ann. NY Acad. Sci. 669 360-207
[10]  
Hankey G(1999)Estimated folate intakes: data updated to reflect food fortification, increased bioavailability, and dietary supplement use Am. J. Clin. Nutr. 70 198-86