Inhibition of gastric emptying and small intestinal transit by ethanol is mediated by capsaicin-sensitive afferent nerves

被引:0
作者
Ferenc Izbéki
Tibor Wittmann
Gábor Jancsó
Sándor Csáti
János Lonovics
机构
[1] First Department of Internal Medicine,
[2] University of Szeged,undefined
[3] Korányi fasor 8,undefined
[4] 6720 Szeged,undefined
[5] Hungary,undefined
[6] Department of Physiology,undefined
[7] University of Szeged,undefined
[8] Dóm tér 10,undefined
[9] 6720 Szeged,undefined
[10] Hungary,undefined
来源
Naunyn-Schmiedeberg's Archives of Pharmacology | 2002年 / 365卷
关键词
Ethanol Capsaicin-sensitive afferent nerves Gastric emptying Small intestinal transit Vagus nerve;
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摘要
The neural mechanisms involved in mediation of the inhibitory effects of ethanol on the gastric emptying and the small intestinal transit were studied in adult male rats. The gastrointestinal transit was determined by measuring the amount of phenol red recovered from the stomach and small intestine after intragastric administration. Spinal and/or vagal peptidergic afferent nerves were subjected to selective denervation by chemodenervation techniques using capsaicin, a potent and specific sensory neurotoxin.
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页码:17 / 21
页数:4
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