An integrated approach of bioinformatic prediction and in vitro analysis identified that miR-34a targets MET and AXL in triple-negative breast cancer

被引:0
作者
Shadan Hajalirezay Yazdi
Mahdi Paryan
Samira Mohammadi-Yeganeh
机构
[1] Islamic Azad University,Department of Cellular and Molecular Biology, Faculty of Advanced Sciences & Technology, Pharmaceutical Sciences Branch
[2] Pasteur Institute of Iran,Department of Research and Development, Production and Research Complex
[3] Shahid Beheshti University of Medical Sciences,Cellular and Molecular Biology Research Center
[4] Shahid Beheshti University of Medical Sciences,Department of Biotechnology, School of Medicine
[5] Shahid Beheshti University of Medical Sciences,Department of Biotechnology, School of Advanced Technologies in Medicine
来源
Cellular & Molecular Biology Letters | 2018年 / 23卷
关键词
Breast cancer; miRNA-34a; Real-time PCR;
D O I
暂无
中图分类号
学科分类号
摘要
引用
收藏
相关论文
共 337 条
[1]  
Liu H(2012)MicroRNAs in breast cancer initiation and progression Cell Mol Life Sci 69 3587-3599
[2]  
Takahashi RU(2015)The roles of MicroRNAs in breast Cancer Cancers (Basel) 7 598-616
[3]  
Miyazaki H(2005)Tyrosine kinases as targets for cancer therapy N Engl J Med 353 172-187
[4]  
Ochiya T(2012)Hedgehog signaling is a novel therapeutic target in tamoxifen-resistant breast cancer aberrantly activated by PI3K/AKT pathway Cancer Res 72 5048-5059
[5]  
Krause DS(2012)Axl-dependent signalling: a clinical update Clin Sci (Lond) 122 361-8
[6]  
Van Etten RA(2011)Identification of the receptor tyrosine kinase AXL in breast cancer as a target for the human miR-34a microRNA Breast Cancer Res Treat 130 663-679
[7]  
Ramaswamy B(2009)Novel therapeutic inhibitors of the c-met signaling pathway in cancer Clin Cancer Res 15 2207-2214
[8]  
Lu Y(2011)Targeting the phosphoinositide-3 (PI3) kinase pathway in breast cancer Oncologist 16 12-19
[9]  
Teng KY(2010)Axl is an essential epithelial-to-mesenchymal transition-induced regulator of breast cancer metastasis and patient survival Proc Natl Acad Sci U S A 107 1124-1129
[10]  
Nuovo G(2015)The clinical and functional significance of c-met in breast cancer: a review Breast Cancer Res 17 52-1544