Hypoglycemic and hepatoprotective effects of Jerusalem artichoke extracts on streptozotocin-induced diabetic rats

被引：1
作者：
Han-Sup Kim
Gi Dong Han
机构：
[1] Yeungnam University,Department of Food Science and Technology, College of Natural Resources
来源：
Food Science and Biotechnology | 2013年 / 22卷
关键词：
anti-diabetic; hepatoprotection; hypoglycemia; Jerusalem artichoke; streptozotocin;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
The effects of Jerusalem artichoke (JA) on hypoglycemia and hepatoprotection in streptozotocin (STZ)-induced diabetic rats were investigated. Water extract of Jerusalem artichoke (JAE) reversed the increase in serum glucose levels in STZ-induced diabetic rats. Further, JAE treatment remarkably prevented elevation of serum aspartate aminotransferase, alanine aminotransferase, lactate dehydrogenase, and γ-glutamyl transpeptidase levels in STZ-induced diabetic rats. Treatment with JAE also improved lipid profiles damaged by STZ in the liver by reducing serum levels of triglycerides and total cholesterol. These results suggest that oral administration of JAE may have a potential benefit of ameliorating diabetic symptoms by improving liver damage caused by STZ. This study gives useful information for understanding the anti-diabetic effect of JA.
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页码：1121 / 1124
页数：3
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