Evidence for compensatory upregulation of expressed X-linked genes in mammals, Caenorhabditis elegans and Drosophila melanogaster

被引：0

作者：

Xinxian Deng

Joseph B Hiatt

Di Kim Nguyen

Sevinc Ercan

David Sturgill

LaDeana W Hillier

Felix Schlesinger

Carrie A Davis

Valerie J Reinke

Thomas R Gingeras

Jay Shendure

Robert H Waterston

Brian Oliver

Jason D Lieb

Christine M Disteche

机构：

[1] University of Washington School of Medicine,Department of Pathology

[2] University of Washington School of Medicine,Department of Genome Sciences

[3] New York University,Department of Biology and Center for Genomics and Systems Biology

[4] Section of Developmental Genomics,Department of Genetics

[5] Laboratory of Cellular and Developmental Biology,Department of Biology

[6] National Institute of Diabetes and Digestive and Kidney Diseases,Department of Medicine

[7] US National Institutes of Health,undefined

[8] Genome Sequencing Center,undefined

[9] Washington University School of Medicine,undefined

[10] Cold Spring Harbor Laboratory,undefined

[11] Cold Spring Harbor,undefined

[12] Yale University,undefined

[13] Carolina Center for the Genome Sciences and Lineberger Comprehensive Cancer Center,undefined

[14] University of North Carolina at Chapel Hill,undefined

[15] University of Washington School of Medicine,undefined

来源：

Nature Genetics | 2011年 / 43卷

关键词：

D O I：

暂无

中图分类号：

学科分类号：

摘要：

Brian Oliver, Jason Lieb, Christine Disteche and colleagues present an analysis of expression data in mammals, C. elegans and Drosophila. They conclude that dosage compensation corrects the imbalance in the number of X chromosomes relative to autosomes by upregulating X-linked genes in both males and females.

引用

页码：1179 / 1185

页数：6

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