Evidence for compensatory upregulation of expressed X-linked genes in mammals, Caenorhabditis elegans and Drosophila melanogaster

被引：0
|
作者：
Xinxian Deng
Joseph B Hiatt
Di Kim Nguyen
Sevinc Ercan
David Sturgill
LaDeana W Hillier
Felix Schlesinger
Carrie A Davis
Valerie J Reinke
Thomas R Gingeras
Jay Shendure
Robert H Waterston
Brian Oliver
Jason D Lieb
Christine M Disteche
机构：
[1] University of Washington School of Medicine,Department of Pathology
[2] University of Washington School of Medicine,Department of Genome Sciences
[3] New York University,Department of Biology and Center for Genomics and Systems Biology
[4] Section of Developmental Genomics,Department of Genetics
[5] Laboratory of Cellular and Developmental Biology,Department of Biology
[6] National Institute of Diabetes and Digestive and Kidney Diseases,Department of Medicine
[7] US National Institutes of Health,undefined
[8] Genome Sequencing Center,undefined
[9] Washington University School of Medicine,undefined
[10] Cold Spring Harbor Laboratory,undefined
[11] Cold Spring Harbor,undefined
[12] Yale University,undefined
[13] Carolina Center for the Genome Sciences and Lineberger Comprehensive Cancer Center,undefined
[14] University of North Carolina at Chapel Hill,undefined
[15] University of Washington School of Medicine,undefined
来源：
Nature Genetics | 2011年 / 43卷
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摘要：
Brian Oliver, Jason Lieb, Christine Disteche and colleagues present an analysis of expression data in mammals, C. elegans and Drosophila. They conclude that dosage compensation corrects the imbalance in the number of X chromosomes relative to autosomes by upregulating X-linked genes in both males and females.
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页码：1179 / 1185
页数：6
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