The Effects of 5-HT4 Receptor Agonist, Mosapride Citrate, on Visceral Hypersensitivity in a Rat Model

被引:0
作者
Jae Woong Lee
Ki Woon Sung
Oh Young Lee
Seo Eun Lee
Chong Il Sohn
机构
[1] Hanil General Hospital,Division of Gastroenterology
[2] Hanyang University,Department of Physiology, College of Medicine
[3] Hanyang University College of Medicine,Department of Internal Medicine
[4] Hanyang University,Department of Biomedical Science, Graduate School of Biomedical Science and Engineering
[5] Sungkyunkwan University School of Medicine,Division of Gastroenterology, Department of Internal Medicine, Kangbuk Samsung Hospital
来源
Digestive Diseases and Sciences | 2012年 / 57卷
关键词
Mosapride citrate; Colorectal distension; Visceral hypersensitivity; Irritable bowel;
D O I
暂无
中图分类号
学科分类号
摘要
引用
收藏
页码:1517 / 1524
页数:7
相关论文
共 145 条
[11]  
Boivin M(2011)Effect of 5-HT(4) receptor agonist mosapride citrate on rectosigmoid sensorimotor function in patients with irritable bowel syndrome Neurogastroenterol Motil 23 754–e332-53
[12]  
Ritchie J(2011)Effects of mosapride citrate, a 5-HT4-receptor agonist, on gastric distension-induced visceromotor response in conscious rats J Pharmacol Sci 116 47-82
[13]  
Sohn CI(2001)Experimental animal models for the study of visceral pain Korean J Gastroenterol 38 77-2068
[14]  
Park HJ(2001)Serotoninergic neuroenteric modulators Lancet 358 2061-1666
[15]  
Gebhart GF(2001)Tegaserod, a 5-HT(4) receptor partial agonist, relieves symptoms in irritable bowel syndrome patients with abdominal pain, bloating and constipation Aliment Pharmacol Ther 15 1655-468
[16]  
Briejer MR(2000)Tegaserod accelerates orocecal transit in patients with constipation-predominant irritable bowel syndrome Gastroenterology 118 463-585
[17]  
Akkermans LM(2003)Tegaserod, a 5-HT4 receptor partial agonist, decreases sensitivity to rectal distension in healthy subjects Aliment Pharmacol Ther 17 577-227
[18]  
Schuurkes JA(2002)Serotonin type-4 receptors modulate the sensitivity of intramural mechanoreceptive afferents of the cat rectum Neurogastroenterol Motil 14 221-180
[19]  
Fink C(1996)5-HT3 and 5-HT4 receptors and cholinergic and tachykininergic neurotransmission in the guinea-pig proximal colon Eur J Pharmacol 308 173-239
[20]  
Tatar M(1996)Stimulation of cyclic AMP formation in the circular smooth muscle of human colon by activation of 5-HT4-like receptors Br J Pharmacol 117 238-1008