Monocyte chemoattractant protein-1 (MCP-1) deficiency enhances alternatively activated M2 macrophages and ameliorates insulin resistance and fatty liver in lipoatrophic diabetic A-ZIP transgenic mice

被引:0
作者
Y. Nio
T. Yamauchi
M. Iwabu
M. Okada-Iwabu
M. Funata
M. Yamaguchi
K. Ueki
T. Kadowaki
机构
[1] Department of Diabetes and Metabolic Diseases,
[2] Graduate School of Medicine,undefined
[3] University of Tokyo,undefined
[4] Department of Integrated Molecular Science on Metabolic Diseases,undefined
[5] 22nd Century Medical and Research Center,undefined
[6] Graduate School of Medicine,undefined
[7] University of Tokyo,undefined
[8] Department of Molecular Medicinal Sciences on Metabolic Regulation,undefined
[9] 22nd Century Medical and Research Center,undefined
[10] Graduate School of Medicine,undefined
[11] University of Tokyo,undefined
来源
Diabetologia | 2012年 / 55卷
关键词
A-ZIP-Tg mice; Extracellular signal-regulated protein kinase; Hepatic steatosis; Insulin signalling; Lipoatrophic diabetes; Macrophage polarisation; Monocyte chemoattractant protein-1;
D O I
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学科分类号
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页码:3350 / 3358
页数:8
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