The outbreak of cryptococcus gattii in western North America: Epidemiology and clinical issues

被引：39

作者：

Byrnes III E.J. ^{[1
,2
]}

Marr K.A. ^{[3
]}

机构：

[1] Department of Medicine, Johns Hopkins University, School of Medicine, Baltimore, MD 21205

[2] Division of Infectious Diseases, Johns Hopkins University, School of Medicine, Baltimore, MD 21205

[3] Transplant and Oncology Infectious Diseases Program, Johns Hopkins University, School of Medicine, Baltimore, MD 21205

来源：

Current Infectious Disease Reports | 2011年 / 13卷 / 3期

关键词：

Cryptococcosis; Fungal outbreak; Meningitis; Pacific Northwest; Pneumonia;

D O I：

10.1007/s11908-011-0181-0

中图分类号：

学科分类号：

摘要：

Over the previous decade, we observed the emergence of the fungal pathogen, Cryptococcus gattii, as a cause of disease in humans and animals in a temperate climate. This outbreak, first documented on Vancouver Island, has since expanded throughout Western North America, with non-travel-associated cases now in British Columbia, Washington, Oregon, and California. Additionally, a secondary outbreak, originating in and still restricted to Oregon, has also occurred. During the past several years, several studies detailing molecular typing, virulence, antifungal susceptibilities, epidemiology, and clinical issues have been published. These studies begin to address the complex dynamics of this novel emergence of a rare and fatal fungus, outline clinical characteristics of human cases, and also opened several new areas that should be explored in the upcoming years. © 2011 Springer Science+Business Media, LLC.

引用

页码：256 / 261

页数：5

共 49 条

[1]

Cohen M.L., Changing patterns of infectious disease, Nature, 406, pp. 762-767, (2000)

[2]

Morens D.M., Folkers G.K., Fauci A.S., The challenge of emerging and re-emerging infectious diseases, Nature, 430, 6996, pp. 242-249, (2004)

[3]

Morens D.M., Folkers G.K., Fauci A.S., Emerging infections: A perpetual challenge, Lancet Infect Dis, 8, pp. 710-719, (2008)

[4]

King D.A., Peckham C., Waage J.K., Brownlie J., Woolhouse M.E.J., Infectious diseases: Preparing for the future, Science, 313, 5792, pp. 1392-1393, (2006)

[5]

Galanis E., MacDougall L., Epidemiology of Cryptococcus gattii, British Columbia, Canada, 1999-2007, Emerg Infect Dis, 16, pp. 251-257, (2010)

[6]

Fisher D., Burrow J., Lo D., Currie B., Cryptococcus neoformans in tropical northern Australia: Predominantly variant gattii with good outcomes, Australian and New Zealand Journal of Medicine, 23, 6, pp. 678-682, (1993)

[7]

Seaton R.A., The management of cryptococcal meningitis in Papua New Guinea, Papua and New Guinea Medical Journal, 1, pp. 67-73, (1996)

[8]

Kwon-Chung K.J., Morphogenesis of Filobasidiella neoformans, the sexual state of Cryptococcus neoformans, Mycologia, 68, pp. 821-833, (1976)

[9]

Kwon-Chung K.J., A new species of Filobasidiella, the sexual state of Cryptococcus neoformans B and C serotypes, Mycologia, 68, pp. 943-946, (1976)

[10]

Casadevall A., Perfect J., Cryptococcus Neoformans, (1998)

← 1 2 3 4 5 →