Electrochemical biosensors for measurement of colorectal cancer biomarkers

被引:0
|
作者
Wenxian Zhang
Guangchun Xiao
Jun Chen
Li Wang
Qiongzheng Hu
Jian Wu
Wenhong Zhang
Ming Song
Jinwei Qiao
Chonghai Xu
机构
[1] Qilu University of Technology (Shandong Academy of Sciences),Advanced Micro and Nano
[2] Qilu University of Technology (Shandong Academy of Sciences),instruments Center, School of Mechanical & Automotive Engineering
来源
Analytical and Bioanalytical Chemistry | 2021年 / 413卷
关键词
Colorectal cancer; Biomarkers; Electrochemical detection; Nanomaterials; Immunosensors; Aptasensors; Genosensor;
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中图分类号
学科分类号
摘要
Colorectal cancer (CRC) is associated with one of the highest rates of mortality among cancers worldwide. The early detection and management of CRC is imperative. Biomarkers play an important role in CRC screening tests, CRC treatment, and prognosis and clinical management; thus rapid and sensitive detection of biomarkers is helpful for early detection of CRC. In recent years, electrochemical biosensors for detecting CRC biomarkers have been widely investigated. In this review, different electrochemical detection methods for CRC biomarkers including immunosensors, aptasensors, and genosensors are summarized. Further, representative examples are provided that demonstrate the advantages of electrochemical sensors modified by various nanomaterials. Finally, the limitations and prospects of biomarkers and electrochemical sensors in detection are also discussed.
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页码:2407 / 2428
页数:21
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