FOXP3 Is a HCC suppressor gene and Acts through regulating the TGF-β/Smad2/3 signaling pathway

被引:0
作者
Jie-Yi Shi
Li-Jie Ma
Ji-Wei Zhang
Meng Duan
Zhen-Bin Ding
Liu-Xiao Yang
Ya Cao
Jian Zhou
Jia Fan
Xiaoming Zhang
Ying-Jun Zhao
Xiao-Ying Wang
Qiang Gao
机构
[1] Liver Cancer Institute,
[2] Zhongshan Hospital,undefined
[3] and Key Laboratory of Carcinogenesis and Cancer Invasion (Ministry of Education),undefined
[4] Fudan University,undefined
[5] Cancer Research Institute,undefined
[6] Fudan University Shanghai Cancer Center,undefined
[7] Cancer Research Institute,undefined
[8] Xiangya School of Medicine,undefined
[9] Central South University,undefined
[10] Institute of Biomedical Sciences,undefined
[11] Fudan University,undefined
[12] Key Laboratory of Molecular Virology & Immunology,undefined
[13] Institut Pasteur of Shanghai,undefined
[14] Chinese Academy of Sciences,undefined
来源
BMC Cancer | / 17卷
关键词
FOXP3; Hepatocellular carcinoma; TGF-β; Prognosis; ChIP;
D O I
暂无
中图分类号
学科分类号
摘要
引用
收藏
相关论文
共 216 条
[21]  
Triulzi T(2012)CXCR6 Upregulation contributes to a proinflammatory tumor microenvironment that drives metastasis and poor patient outcomes in hepatocellular carcinoma Cancer Res 72 5994-6005
[22]  
Tagliabue E(2013)Margin-infiltrating CD20(+) B cells display an atypical memory phenotype and correlate with favorable prognosis in hepatocellular carcinoma Clin Cancer Res 19 872-879
[23]  
Balsari A(2010)PEBP1 Downregulation is associated to poor prognosis in HCC related to hepatitis B infection J Hepatol 53 971-979
[24]  
Casalini P(2009)Overexpression of PD-L1 significantly associates with tumor aggressiveness and postoperative recurrence in human hepatocellular carcinoma Clinical cancer research: an official journal of the American Association for Cancer Research 15 829-834
[25]  
Merlo A(2008)Genome-wide analysis of transcription factor binding sites based on ChIP-Seq data Nat Methods 5 3001-3009
[26]  
Casalini P(2008)The regulatory T cell-associated transcription factor FoxP3 is expressed by tumor cells Cancer Res 68 770-784
[27]  
Carcangiu ML(2011)FOXP3 Orchestrates H4K16 acetylation and H3K4 trimethylation for activation of multiple genes by recruiting MOF and causing displacement of PLU-1 Mol Cell 44 1057-1061
[28]  
Malventano C(2003)Control of regulatory T cell development by the transcription factor Foxp3 Science 299 1045-1054
[29]  
Triulzi T(2012)FOXP3 And FOXP3-regulated microRNAs suppress SATB1 in breast cancer cells Oncogene 31 625-632
[30]  
Menard S(2013)FOXP3 Expression in tumor cells and tumor-infiltrating lymphocytes is associated with breast cancer prognosis Mol Clin Oncol 1 3133-3142