Neurolymphomatosis: a rare metastatic complication of diffuse large B-Cell lymphoma

被引：0
作者：
Marc C. Chamberlain
James Fink
机构：
[1] University of Washington,Department of Neurology and Neurological Surgery, Fred Hutchinson Cancer Research Institute, Seattle Cancer Care Alliance
[2] University of Washington,Department of Radiology
来源：
Journal of Neuro-Oncology | 2009年 / 95卷
关键词：
Neurolymphomatosis; Upper and lower limb plexus;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
To report the occurrence of neurolymphomatosis in a patient with previously treated systemic diffuse B-cell lymphoma (DLBCL). A case report. University medical center. A 54-year old woman with previously treated DLBCL developed sequential mono-, di- and triparesis 3-months after completion of systemic therapy. MR of lumbar and brachial plexus revealed diffuse involvement of nerve roots and plexus. High-dose methotrexate and involved-field radiotherapy. Neurolymphomatosis, although rare, is increasingly recognized with peripheral and central nervous system MRI. Treatment remains unsatisfactory as treatment with methotrexate-based chemotherapy and irradiation is only partially effective.
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页码：285 / 288
页数：3
相关论文
共 42 条
[1]  
Currie S(1971)Neurological syndromes in the reticuloses Brain 94 307-320
[2]  
Henson RA(1992)Neurolymphomatosis: a clinicopathological syndrome re-emerges Neurology 42 1136-1141
[3]  
Diaz-Arrastia R(2001)Neurolymphomatosis associated with muscle and cerebral involvement caused by natural killer cell lymphoma: a case report and review of the literature J Peripher Nerv Syst 6 197-203
[4]  
Younger DS(2003)Neurolymphomatosis Neuro-oncol 5 104-115
[5]  
Hair L(2004)High dose intravenous methotrexate followed by autologous stem cell transplantation as potentially effective therapy for neurolymphomatosis Cancer 100 2403-2407
[6]  
Odabasi Z(1996)Neurolymphomatosis Neurology 46 1191-1192
[7]  
Parrott JH(2005)Lymphoma and peripheral neuropathy: a clinical review Muscle Nerve 31 301-313
[8]  
Reddy VV(2000)Primary lymphoma of peripheral nerve: report of four cases Am J Surg Pathol 24 1257-1265
[9]  
Baehring JM(1997)Primary non-Hodgkin’s lymphoma of the sciatic nerve followed by localization in the central nervous system: case report and review of the literature Neurosurgery 40 618-621
[10]  
Damek D(2001)Neurolymphomatosis of the lumbar plexus: high resolution MR neuroradiography findings Neurology 57 740-742
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