Allergy preventionInterventions during pregnancy and early infancy

被引：0
作者：
Bengt Björkstén
机构：
[1] Karolinska Institutet,Center for Allergy Research and Department of Environmental Medicine
来源：
Clinical Reviews in Allergy & Immunology | 2004年 / 26卷
关键词：
Allergy prevention; dust mites; environmental exposure; nutrition;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
The increase in allergic disease in western, industrialized countries has been phenomenal. Although the reasons for this increase are unknown, it is clear that the primary management of allergies is prevention. There is now significant epidemiologic data suggesting that a program designed and focused on prevention will have a significant impact on the development of allergies. These include not only environmental, but also dietary restrictions. There remain, however, several major problems. Firstly, it is not clear which subjects will respond best to a program focusing on either pre—or postnatal prevention. Secondly, the immunological mechanisms involved remain unclear. For example, it would be highly desirable to have a readout that monitors the improvement in allergen avoidance, other than clinical response. This review will focus on the immunological background of alleregy prevention, including epidemiologic observations and thoughts for future potential allergy prevention.
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页码：129 / 138
页数：9
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