The emerging role of microRNAs in multiple sclerosis

被引：0
作者：
Andreas Junker
Reinhard Hohlfeld
Edgar Meinl
机构：
[1] University Medical Center,Department of Neuropathology
[2] Georg August University,undefined
[3] Institute of Clinical Neuroimmunology,undefined
[4] Ludwig Maximilian University of Munich,undefined
来源：
Nature Reviews Neurology | 2011年 / 7卷
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学科分类号：
摘要：
MicroRNAs (miRNAs) seem to confer a novel layer of gene regulation, possibly fine-tuning the expression of ≈50% of genes in humans. Dysfunction of these short regulatory RNAs has been noted in various neurological disorders, including Alzheimer disease and Parkinson disease. Here, Junker and colleagues explore the possible involvement of miRNAs in multiple sclerosis, highlighting the therapeutic implications for this disease.
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页码：56 / 59
页数：3
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