Human herpesvirus 8: Biology and role in the pathogenesis of Kaposi’s sarcoma and other aids-related malignancies

被引：14
作者：
Viejo-Borbolla A. [1 ]
Ottinger M. [1 ]
Schulz T.F. [1 ]
机构：
[1] Department of Virology, Hannover Medical School, Carl-Neuberg-Str.1, Hannover
来源：
Current HIV/AIDS Reports | 2004年 / 1卷 / 1期
关键词：
KSHV Gene; KSHV Genome; Plasma Cell Variant; Primary Effusion Lymphoma; Primary Effusion Lymphoma Cell;
D O I：
10.1007/s11904-004-0001-3
中图分类号：
学科分类号：
摘要：
Human herpesvirus type 8, or Kaposi’s sarcoma-associated herpesvirus (KSHV), is the only known human γ 2 herpesvirus (rhadinovirus) and the most recently discovered tumor virus. KSHV is associated with Kaposi’s sarcoma and two other lymphoproliferative disorders in the AIDS setting: primary effusion lymphoma and the plasma cell variant of multicentric Castleman’s disease. This review offers an update on the epidemiology and the role of KSHV genes in the development of disease. © 2004, Current Science Inc.
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页码：5 / 11
页数：6
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