Factors affecting FEV1 in workers with potroom asthma after their removal from exposure

被引：0
作者：
Sorgdrager B. [1 ]
De Looff A.J.A. [3 ]
Pal T.M. [4 ]
Van Dijk F.J.H. [2 ]
De Monchy J.G.R. [1 ]
机构：
[1] Department of Allergology, University Hospital, Groningen
[2] Netherlands Center of Occupational Diseases, Coronel Instituut, Academic Medical Centre, Meibergdreef 15
[3] Occupational Health Service, Zeeland, Vlissingen
[4] Department of Social Medicine, Groningen University
来源：
International Archives of Occupational and Environmental Health | 2000年 / 74卷 / 1期
关键词：
Asthma; Prognostic Factor; Medical Treatment; Exposure Time; Confounding Factor;
D O I：
10.1007/s004200000180
中图分类号：
学科分类号：
摘要：
Objective: In this study the relationship has been studied between exposure time and potential prognostic factors and FEV1 percent predicted (FEV1-% pred) in workers with potroom asthma, after their transfer from exposure to exposure-free departments. Methods: Between 1970 and 1990 in a Dutch aluminium-production plant, 179 workers had been diagnosed as having potroom asthma. We carried out a follow-up study (n = 122) in the population still present at the factory 5 years after their relocation to an exposure-free department. In this study population, we examined the relationship between FEV1-% pred at follow-up, and exposure time: the time interval between start of exposure and diagnosis. To correct for confounding factors, we included age, pre-employment FEV1-% pred, allergy, medical treatment, and smoking in the analysis. Results: The mean FEV1-% pred at follow-up was within the normal range (90.3, SD 13.5). Long exposure time was significantly associated with a low FEV1-% pred at follow-up (P = 0.0046). Adjustment was necessary for pre-employment FEV1-% pred and current smoking as confounding factors. Conclusion: Long duration of exposure is a factor affecting FEV1 in workers with potroom asthma. The results of this study give support for additional preventive measures to be taken, such as early recognition of work-related respiratory complaints and repeated education.
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页码：55 / 58
页数：3
相关论文
共 14 条
  • [1] Abramson, M.J., Wlodarczyk, J.H., Saunders, N.A., Hensley, M.J., Does aluminium smelting cause lung disease? State of the art (1989) Am Rev Respir Dis, 13, pp. 1042-1057
  • [2] Kongerud, J., Boe, J., Søyseth, V., Naalsund, A., Magnus, P., Aluminium potroom asthma: The Norwegian experience (1994) Eur Respir J, 7, pp. 165-172
  • [3] Sorgdrager, B., Pal, T.M., De Looff, A.J.A., Dubois, A.E.J., De Monchy, J.G.R., Occupational asthma in aluminium potroom workers related to pre-employment eosinophil count (1995) Eur Respir J, 8, pp. 1520-1524
  • [4] Sorgdrager, B., De Looff, A.J.A., De Monchy, J.G.R., Pal, T.M., Dubois, A.E.J., Rijcken, B., The occurrence of occupational asthma in aluminium potroom workers in relation with preventive measures (1998) Int Arch Occup Environ Health, 71, pp. 53-59
  • [5] Yeung, M., Grzybowsky, S., Prognosis in occupational asthma (1985) Thorax, 40, pp. 241-243. , Editorial
  • [6] Soyseth, V., Kongerud, J., Bronchial responsiveness and work related asthma in aluminium potroom workers: Effect of removal from exposure (1992) Eur Respir J, 5, pp. 829-833
  • [7] Wergeland, E., Lund, E., Waage, J.E., Respiratory dysfunction after potroom asthma (1987) Am J Ind Med, 11, pp. 627-636
  • [8] Gispen, J.G.W., Respiratory problems at Pechiney Nederland (1980) Seminar on Aluminium Respiratory Disorders, pp. 49-57. , In: Coulon JP (ed)
  • [9] St Nicolas Aluminium, Greece
  • [10] Quanjer, P.H., Standardized lung function testing. Report by the working party of the European Community for Coal and Steel (1983) Bull Eur Physiopathol Respir, 19 (SUPPL. 5), pp. 1-95
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