Embryonic stem cells require Wnt proteins to prevent differentiation to epiblast stem cells

被引：0
作者：
Derk ten Berge
Dorota Kurek
Tim Blauwkamp
Wouter Koole
Alex Maas
Elif Eroglu
Ronald K. Siu
Roel Nusse
机构：
[1] Erasmus MC Stem Cell Institute,Department of Cell Biology
[2] Erasmus Medical Center,and Department of Developmental Biology
[3] Howard Hughes Medical Institute,Department of Cell Biology
[4] Stanford University School of Medicine,undefined
[5] Erasmus Medical Center,undefined
来源：
Nature Cell Biology | 2011年 / 13卷
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学科分类号：
摘要：
ten Berge and colleagues show that Wnt signalling is required for self-renewal of embryonic stem cells through inhibition of their differentiation into epiblast stem cells. Together, Wnt and LIF signalling can support derivation and self-renewal of embryonic stem cells.
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页码：1070 / 1075
页数：5
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