Tumorous IRE1α facilitates CD8+T cells-dependent anti-tumor immunity and improves immunotherapy efficacy in melanoma

被引:0
作者
Yuqi Yang
Sijia Wang
Xiang-xu Wang
Sen Guo
Huina Wang
Qiong Shi
Yangzi Tian
Hao Wang
Tao Zhao
Hengxiang Zhang
Baolu Zhang
Tianwen Gao
Chunying Li
Xiuli Yi
Weinan Guo
机构
[1] Fourth Military Medical University,Department of Dermatology, Xijing Hospital
[2] Southern Medical University,Department of Dermatology, Nanfang Hospital
[3] Xijing Hospital,Department of Clinical Oncology
[4] Fourth Military Medical University,undefined
来源
Cell Communication and Signaling | / 22卷
关键词
ER stress; Melanoma; Immunosurveillance; Immunotherapy; Anti-PD-1 antibody;
D O I
暂无
中图分类号
学科分类号
摘要
引用
收藏
相关论文
共 507 条
[1]  
Lo JA(2014)The melanoma revolution: from UV carcinogenesis to a new era in therapeutics Science 346 945-9
[2]  
Fisher DE(2021)Signal pathways of melanoma and targeted therapy Signal Transduct Target Ther 6 424-8
[3]  
Guo W(2019)A review of exosomes and their role in the Tumor Microenvironment and Host-Tumor Macroenvironment J Immunol Sci 3 4-34
[4]  
Wang H(2019)Melanoma-derived extracellular vesicles instigate proinflammatory signaling in the metastatic microenvironment Int J Cancer 145 2521-904
[5]  
Li C(2017)PD-L1 on tumor cells is sufficient for immune evasion in immunogenic tumors and inhibits CD8 T cell cytotoxicity J Exp Med 214 895-37
[6]  
Tung KH(2022)Long-term outcomes with Nivolumab Plus Ipilimumab or Nivolumab alone Versus Ipilimumab in patients with Advanced Melanoma J Clin Oncol 40 127-69
[7]  
Ernstoff MS(2020)Mutant BRAF and MEK inhibitors regulate the Tumor Immune Microenvironment via Pyroptosis Cancer Discov 10 254-87
[8]  
Allen C(2021)KDM5B promotes immune evasion by recruiting SETDB1 to silence retroelements Nature 598 682-39
[9]  
Shu S(2022)Endoplasmic reticulum stress in liver diseases Hepatology 77 619-505
[10]  
Gener Lahav T(2017)Emerging role of the unfolded protein response in Tumor Immunosurveillance Trends Cancer 3 491-43e12