The advances and perspectives of recombinant protein production in the silk gland of silkworm Bombyx mori

被引：0
作者：
Hanfu Xu
机构：
[1] Southwest University,State Key Laboratory of Silkworm Genome Biology
来源：
Transgenic Research | 2014年 / 23卷
关键词：
Silkworm; Silk gland; Expression system; Recombinant protein; Silk-based biomaterial;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
The silk gland of silkworm Bombyx mori, is one of the most important organs that has been fully studied and utilized so far. It contributes finest silk fibers to humankind. The silk gland has excellent ability of synthesizing silk proteins and is a kind tool to produce some useful recombinant proteins, which can be widely used in the biological, biotechnical and pharmaceutical application fields. It’s a very active area to express recombinant proteins using the silk gland as a bioreactor, and great progress has been achieved recently. This review recapitulates the progress of producing recombinant proteins and silk-based biomaterials in the silk gland of silkworm in addition to the construction of expression systems. Current challenges and future trends in the production of valuable recombinant proteins using transgenic silkworms are also discussed.
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页码：697 / 706
页数：9
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