Synthesis and study of antibacterial and antifungal activities of Novel 2-[[(benzoxazole/benzimidazole-2-yl)sulfanyl] acetylamino]thiazoles

被引：0

作者：

Zafer Asim Kaplancikli

Gülhan Turan-Zitouni

Gilbert Revial

Kiymet Guven

机构：

[1] CNRS (ESA 7084) ESPCI,Laboiratoire de Chimie Organique

[2] Anadolu University,Department of Biology

[3] Faculty of Science,Department of Pharmaceutical Chemistry

[4] Anadolu University,undefined

[5] Faculty of Pharmacy,undefined

来源：

Archives of Pharmacal Research | 2004年 / 27卷

关键词：

Thiazole; Benzoxazole; Benzimidazole; Antimicrobial activity;

D O I：

暂无

中图分类号：

学科分类号：

摘要：

Several 2-[[(benzoxazole/benzimidazole-2-yl)sulfanyl]acetylamino]thiazoles derivatives were synthesized by reacting 4-substituted-2-(chloroacetylamino)thiazoles with benzoxazole/benzimidazole-2-thioles in acetone and in the presence of K2CO3. The chemical structures of the compounds were elucidated by IR,1H-NMR, and FAB+-MS spectral data. Their antimicrobial activities againstMicrococcus luteus (NRLL B-4375),Bacillus cereus (NRRL B-3711),Proteus vulgaris (NRRL B-123),Salmonella typhimurium (NRRL B-4420),Staphylococcus aureus (NRRL B-767),Escherichia coli (NRRL B-3704),Candida albicans and Candida globrata (isolates obtained from Osmangazi Uni. Fac.of Medicine) were investigated and in this investigation, a significant level of activity was illustrated.

引用

页码：1081 / 1085

页数：4

共 50 条

[31] Synthesis and Evaluation of Antibacterial and Anticancer Activities of Some New Benzoxazole-Piperazine-1,2,3-Triazoles
Vidya, K.
INDIAN JOURNAL OF HETEROCYCLIC CHEMISTRY, 2020, 30 (02) : 269 - 274
[32] Convenient and green synthesis of novel 1,2,5-trisubstituted benzimidazole compounds and their antibacterial activity evaluation
Liu, Kejun
Luo, Rui
Fu, Jiaxu
Bao, Lijian
Xue, Yafei
Gu, Qiang
Zhang, Yumin
Lin, Feng
JOURNAL OF THE IRANIAN CHEMICAL SOCIETY, 2023, 20 (05) : 1095 - 1105
[33] Convenient and green synthesis of novel 1,2,5-trisubstituted benzimidazole compounds and their antibacterial activity evaluation
Kejun Liu
Rui Luo
Jiaxu Fu
Lijian Bao
Yafei Xue
Qiang Gu
Yumin Zhang
Feng Lin
Journal of the Iranian Chemical Society, 2023, 20 : 1095 - 1105
[34] Sythesis Of Novel 2-Thioxo-4-Imidazolidinone Derivatives And Evaluate Their Antibacterial, And Antifungal Activities
AbdulJabar, Layla Adnan
Mutalq, Dakhil Zughayir
Al-Shawi, Ali A. A.
EGYPTIAN JOURNAL OF CHEMISTRY, 2021, 64 (06): : 3059 - 3067
[35] Synthesis and Antifungal Activity of Novel 2-(1H-Benzimidazol-2-yl)-5-substituted-1,3,4-oxadiazole Derivatives
Ji, Zengchen
Liu, Feng
Zhang, Zeyuan
Li, Fubo
Jiang, Lin
CHINESE JOURNAL OF ORGANIC CHEMISTRY, 2012, 32 (11) : 2129 - 2133
[36] Synthesis of 2,3-Bis(halomethyl)quinoxaline Derivatives and Evaluation of Their Antibacterial and Antifungal Activities
Ishikawa, Hisato
Sugiyama, Takayuki
Yokoyama, Akihiro
CHEMICAL & PHARMACEUTICAL BULLETIN, 2013, 61 (04) : 438 - 444
[37] Synthesis of CuS and ZnO/Zn(OH)2 nanoparticles and their evaluation for in vitro antibacterial and antifungal activities
Khafri, Hossein Zare
Ghaedi, Mehrorang
Asfaram, Arash
Javadian, Hamedreza
Safarpoor, Mohammad
APPLIED ORGANOMETALLIC CHEMISTRY, 2018, 32 (07)
[38] Synthesis, in silico studies and antibacterial activity of some novel 2-substituted benzimidazole derivatives
Chintakunta, Ramakrishna
Meka, Geethavani
FUTURE JOURNAL OF PHARMACEUTICAL SCIENCES, 2020, 6 (01)
[39] SYNTHESIS AND CRYSTAL STRUCTURE OF COBALT(III) COMPLEXES WITH SUBSTITUTED 2-[(BENZIMIDAZOLE-1-YL) IMINOMETHYL]PHENOLS
Burlov, A. S.
Kuzmenko, T. A.
Vlasenko, V. G.
Koshchienko, Yu, V
Mashchenko, S. A.
Chaltsev, B., V
Kolodina, A. A.
Kiskin, M. A.
JOURNAL OF STRUCTURAL CHEMISTRY, 2021, 62 (12) : 1946 - 1954
[40] SYNTHESIS AND CRYSTAL STRUCTURE OF COBALT(III) COMPLEXES WITH SUBSTITUTED 2-[(BENZIMIDAZOLE-1-YL) IMINOMETHYL]PHENOLS
A. S. Burlov
T. A. Kuzmenko
V. G. Vlasenko
Yu. V. Koshchienko
S. A. Mashchenko
B. V. Chaltsev
A. A. Kolodina
M. A. Kiskin
Journal of Structural Chemistry, 2021, 62 : 1946 - 1954

← 1 2 3 4 5 →