Synthesis and study of antibacterial and antifungal activities of Novel 2-[[(benzoxazole/benzimidazole-2-yl)sulfanyl] acetylamino]thiazoles

被引：0
|
作者：
Zafer Asim Kaplancikli
Gülhan Turan-Zitouni
Gilbert Revial
Kiymet Guven
机构：
[1] CNRS (ESA 7084) ESPCI,Laboiratoire de Chimie Organique
[2] Anadolu University,Department of Biology
[3] Faculty of Science,Department of Pharmaceutical Chemistry
[4] Anadolu University,undefined
[5] Faculty of Pharmacy,undefined
来源：
Archives of Pharmacal Research | 2004年 / 27卷
关键词：
Thiazole; Benzoxazole; Benzimidazole; Antimicrobial activity;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Several 2-[[(benzoxazole/benzimidazole-2-yl)sulfanyl]acetylamino]thiazoles derivatives were synthesized by reacting 4-substituted-2-(chloroacetylamino)thiazoles with benzoxazole/benzimidazole-2-thioles in acetone and in the presence of K2CO3. The chemical structures of the compounds were elucidated by IR,1H-NMR, and FAB+-MS spectral data. Their antimicrobial activities againstMicrococcus luteus (NRLL B-4375),Bacillus cereus (NRRL B-3711),Proteus vulgaris (NRRL B-123),Salmonella typhimurium (NRRL B-4420),Staphylococcus aureus (NRRL B-767),Escherichia coli (NRRL B-3704),Candida albicans and Candida globrata (isolates obtained from Osmangazi Uni. Fac.of Medicine) were investigated and in this investigation, a significant level of activity was illustrated.
引用
收藏
页码：1081 / 1085
页数：4
相关论文
共 50 条
  • [1] Synthesis and study of antibacterial and antifungal activities of novel 2-[[(benzoxazole/benzimidazole-2-yl)sulfanyl] acetylamino]thiazoles
    Kaplancikli, ZA
    Turan-Zitouni, G
    Revial, G
    Guven, K
    ARCHIVES OF PHARMACAL RESEARCH, 2004, 27 (11) : 1081 - 1085
  • [2] Synthesis and study of antibacterial and antifungal activities of novel 1-[2-(benzoxazol-2-yl)ethoxy]-2,6-diarylpiperidin-4-ones
    Ramalingan, C
    Balasubramanian, S
    Kabilan, S
    Vasudevan, A
    EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2004, 39 (06) : 527 - 533
  • [3] SYNTHESIS OF SOME 2-(ACETOPHENON-HYDRAZIN)-THIAZOLES AND 2-(4-THIAZOLYL-METHYNHYDRAZIN)-THIAZOLES AS POTENTIAL ANTIBACTERIAL AND ANTIFUNGAL AGENTS
    Oniga, Ovidiu
    Moldovan, Cristina
    Oniga, Smaranda
    Tiperciuc, Brindusa
    Parnau, Adrian
    Verite, Philippe
    Crisan, Ovidiu
    Ionut, Ioana
    FARMACIA, 2010, 58 (06) : 825 - 833
  • [4] Design, Synthesis, Molecular Docking and Biological Evaluation of Novel 2-[(2-{[5-(Pyridin-4-yl)-1, 3, 4-Oxadiazol-2-yl]Sulfanyl}Ethyl)Sulfanyl]-1,3-Benzoxazole
    Fathima, Anees
    Vagdevi, H. M.
    Jayanna, N. D.
    Shafeeulla, R. Mohammed
    Subbaraju
    JOURNAL OF PHARMACEUTICAL RESEARCH INTERNATIONAL, 2021, 33 (44A) : 472 - 484
  • [5] Synthesis and antiprotozoal activity of novel 2-{[2-(1H-imidazol-1-yl)ethyl] sulfanyl}-1H-benzimidazole derivatives
    Perez-Villanueva, Jaime
    Hernandez-Campos, Alicia
    Yepez-Mulia, Lilian
    Mendez-Cuesta, Carlos
    Mendez-Lucio, Oscar
    Hernandez-Luis, Francisco
    Castillo, Rafael
    BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2013, 23 (14) : 4221 - 4224
  • [6] Synthesis, characterization, and antibacterial activities of two new copper(II) glycinate complexes incorporating 2-(4′-thiazolyl)benzimidazole/2-(2-pyridyl)benzimidazole
    Chen, Jia Yang
    Ren, Xiang Xiang
    Mao, Zong Wan
    Le, Xue Yi
    JOURNAL OF COORDINATION CHEMISTRY, 2012, 65 (12) : 2182 - 2191
  • [7] Synthesis and antimicrobial activity of novel 2-substituted benzimidazole, benzoxazole and benzothiazole derivatives
    Padalkar, Vikas S.
    Borse, Bhushan N.
    Gupta, Vinod D.
    Phatangare, Kiran R.
    Patil, Vikas S.
    Umape, Prashant G.
    Sekar, N.
    ARABIAN JOURNAL OF CHEMISTRY, 2016, 9 : S1125 - S1130
  • [8] Synthesis of 2-Pyridin-3-yl-1,3-benzoxazole and 2-Pyridin-3-yl-1,3-benzimidazole under Microwave Irradiation and Their Antimicrobial Evaluation
    Valarmathy, J.
    Joshua, L. Samuel
    ASIAN JOURNAL OF CHEMISTRY, 2009, 21 (03) : 1797 - 1800
  • [9] Synthesis and antimicrobial activity of some novel 2,5- and/or 6-substituted benzoxazole and benzimidazole derivatives
    Ören, I
    Temiz, Ö
    Yalçin, I
    Sener, E
    Altanlar, N
    EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, 1999, 7 (02) : 153 - 160
  • [10] Structure, Antibacterial Activities and DNA Interaction of a Copper(II) Complex with 2-(2′-Pyridyl) benzoxazole and Glycinate
    Ou Zhi-Bin
    Huang Shan-Hua
    Le Xue-Yi
    CHINESE JOURNAL OF INORGANIC CHEMISTRY, 2012, 28 (08) : 1580 - 1586
12345