A mitotic role for the DNA damage-responsive CHK2 kinase

被引：0

作者：

Ko Sato

Tomohiko Ohta

Ashok R. Venkitaraman

机构：

[1] University of Cambridge,Ko Sato and Ashok R. Venkitaraman are in the Department of Oncology and the Medical Research Council Cancer Cell Unit

[2] Hutchison/MRC Research Centre,Tomohiko Ohta is in the Department of Translational Oncology

[3] Hills Road,undefined

[4] Cambridge,undefined

[5] CB2 0XZ arv22@hutchison-mrc.cam.ac.uk,undefined

[6] St Marianna University Graduate School of Medicine,undefined

[7] 2-16-1 Sugao,undefined

[8] Miyamae,undefined

[9] Kawasaki,undefined

[10] 216-8511,undefined

[11] Japan.,undefined

来源：

Nature Cell Biology | 2010年 / 12卷

关键词：

D O I：

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中图分类号：

学科分类号：

摘要：

Instability in the structure and number of chromosomes is a trait common to cells from most epithelial cancers. A role in chromosome segregation for a pathway previously implicated in the DNA damage response reveals new connections between the tumour suppressive processes that maintain chromosome integrity.

引用

页码：424 / 425

页数：1

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