A mitotic role for the DNA damage-responsive CHK2 kinase

被引：0
|
作者：
Ko Sato
Tomohiko Ohta
Ashok R. Venkitaraman
机构：
[1] University of Cambridge,Ko Sato and Ashok R. Venkitaraman are in the Department of Oncology and the Medical Research Council Cancer Cell Unit
[2] Hutchison/MRC Research Centre,Tomohiko Ohta is in the Department of Translational Oncology
[3] Hills Road,undefined
[4] Cambridge,undefined
[5] CB2 0XZ arv22@hutchison-mrc.cam.ac.uk,undefined
[6] St Marianna University Graduate School of Medicine,undefined
[7] 2-16-1 Sugao,undefined
[8] Miyamae,undefined
[9] Kawasaki,undefined
[10] 216-8511,undefined
[11] Japan.,undefined
来源：
Nature Cell Biology | 2010年 / 12卷
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摘要：
Instability in the structure and number of chromosomes is a trait common to cells from most epithelial cancers. A role in chromosome segregation for a pathway previously implicated in the DNA damage response reveals new connections between the tumour suppressive processes that maintain chromosome integrity.
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页码：424 / 425
页数：1
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